Humans consume a wide range of foods, drugs, and dietary supplements that are derived
from plants and which modify the functioning of the central nervous sytem (CNS). The …

Rationale and objective Empirical studies indicate that nicotine enhances some aspects of
attention and cognition, suggesting a role in the maintenance of tobacco dependence. The …

Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

BACKGROUND: A nonsynonymous coding polymorphism, rs16969968, of the CHRNA5
gene that encodes the alpha-5 subunit of the nicotinic acetylcholine receptor (nAChR) has …

We're all familiar with the idea that plant-derived chemicals can have an impact on the
functioning of the human brain. Most of us reach for a cup of coffee or tea in the morning …

Subjective alertness and optimal cognitive function, including in terms of attention,
spatial/working memory and executive function, are intrinsic to peak performance in many …

Tobacco smoking is a serious health problem worldwide and a leading cause of mortality.
Nicotine, the addictive component of tobacco, affects a range of emotional responses …

Altered cholinergic neural transmission is hypothesized to increase susceptibility to
cognitive deficits in psychotic disorders such as schizophrenia (SCZ). The nicotinic …

Intravenous nicotine self-administration is the most direct measure of nicotine reinforcement
in laboratory animals, but this procedure has proven difficult to establish in mice. We found …

Rationale It is well established that nicotine improves, and deprivation impairs, cognitive
performance and mood in smokers. Prospective memory (PM), remembering to execute a …