Biodegradation of MC-LR and its key bioactive moiety Adda by Sphingopyxis sp. YF1: Comprehensive elucidation of the mechanisms and pathways

J Wei, Z Pengji, J Zhang, T Peng, J Luo, F Yang - Water Research, 2023 - Elsevier
Microcystins (MCs) are harmful to the ecology and public health. Some bacteria can
degrade MCs into Adda, but few can destroy Adda. Adda is the key bioactive moiety of MCs …

Robust ω-transaminases by computational stabilization of the subunit interface

Q Meng, N Capra, CM Palacio, E Lanfranchi… - ACS …, 2020 - ACS Publications
Transaminases are attractive catalysts for the production of enantiopure amines. However,
the poor stability of these enzymes often limits their application in biocatalysis. Here, we …

[HTML][HTML] Comprehensive genomic and transcriptomic analyses of the anaerobic degradation of microcystin in Alcaligenes faecalis D04

F Yang, L Yang, J Wei, T Ma, M Zhou, L Liao… - Ecotoxicology and …, 2025 - Elsevier
Abstract Microcystin LR (MC-LR) pollution is a serious threat to aquatic ecosystems and
public health in China and is an environmental problem that urgently needs to be solved …

Asymmetric synthesis of optically pure aliphatic amines with an engineered robust ω-transaminase

L Dong, Q Meng, C Ramírez-Palacios, HJ Wijma… - Catalysts, 2020 - mdpi.com
The production of chiral amines by transaminase-catalyzed amination of ketones is an
important application of biocatalysis in synthetic chemistry. It requires transaminases that …

A single amino acid substitution alters the vanillylamine synthesis activity of Capsicum pAMT

K Sano, S Nakasato, K Nagata, K Kobata - Biochemical and Biophysical …, 2023 - Elsevier
Some Capsicum synthesize a unique pungent alkaloid called capsaicin in their fruits. In the
synthetic pathway of capsaicin, vanillylamine is produced from vanillin in a reaction …

The crystal structure of the tetrameric DABA‐aminotransferase EctB, a rate‐limiting enzyme in the ectoine biosynthesis pathway

HT Hillier, B Altermark, I Leiros - The FEBS Journal, 2020 - Wiley Online Library
l‐2, 4‐diaminobutyric acid (DABA) aminotransferases can catalyze the formation of amines
at the distal ω‐position of substrates, and is the intial and rate‐limiting enzyme in the …

Redox self-sufficient production of hydroxytyrosol from dopamine by enzymatic cascade catalysis

Y Yan, Y Bai, X Zheng, Y Cai - Biochemical Engineering Journal, 2023 - Elsevier
Due to its powerful antioxidant capacity, hydroxytyrosol (HT) has a long history of application
in the cosmetics and food industries. Owing to the fact that current isolation procedures for …

Catalytic and structural properties of ATP‐dependent caprolactamase from Pseudomonas jessenii

A Marjanovic, HJ Rozeboom… - Proteins: Structure …, 2021 - Wiley Online Library
Caprolactamase is the first enzyme in the caprolactam degradation pathway of
Pseudomonas jessenii. It is composed of two subunits (CapA and CapB) and sequence …

Unveiling the Multipath Biosynthesis Mechanism of 2-Phenylethanol in Proteus mirabilis

J Liu, Y Bai, T Fan, X Zheng, Y Cai - Journal of Agricultural and …, 2020 - ACS Publications
Proteus mirabilis could convert l-phenylalanine into 2-phenylethanol (2-PE) via the Ehrlich
pathway, the amino acid deaminase pathway, and the aromatic amino acid decarboxylase …

Epsilon-Caprolactam- and Nylon Oligomer-Degrading Bacterium Brevibacterium epidermidis BS3: Characterization and Potential Use in Bioremediation

TZ Esikova, EV Akatova, IP Solyanikova - Microorganisms, 2023 - mdpi.com
epsilon-Caprolactam (Caprolactam, CAP), a monomer of the synthetic non-degradable
polymer nylon-6, is the major wastewater component in the production of caprolactam and …