Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies

MV Giolito, S Bodoirat, T La Rosa, M Reslinger… - Cell Death & …, 2024 - nature.com
Colorectal cancers (CRCs) are highly heterogeneous and show a hierarchical organization,
with cancer stem cells (CSCs) responsible for tumor development, maintenance, and drug …

Deciphering the role of intestinal crypt cell populations in resistance to chemotherapy

C Frau, C Jamard, G Delpouve, GDA Guardia… - Cancer Research, 2021 - AACR
Intestinal crypts are composed of heterogeneous and highly plastic cell populations.
Lgr5high-stem cells (SC) are responsible for homeostatic renewal, but other cells can revert …

Mimicking the Tumor Niche: Methods for Isolation, Culture, and Characterization of Cancer Stem Cells and Multicellular Spheroids

L De Lara-Pena, C Farace, A Pisano… - Cancer Stem Cells …, 2024 - Springer
Cancer stem cells (CSCs) play a significant role in driving several tumor hallmarks. Their
behavior and tumor progression are strictly related to the tumor microenvironment (TME) …

Le code-barres Rouge-Vert-Bleu (RVB): Un modèle fluorescent de suivi du lignage cellulaire pour déchiffrer la fonction du récepteur nucléaire de l'hormone …

L Claret - 2022 - ephe.hal.science
Nos études précédentes ont mis en évidence les rôles clés du récepteur nucléaire de
l'hormone thyroïdienne TRα1 dans le contrôle de la biologie des cellules …

[PDF][PDF] Normal Cell Differentiation Potential of Cancer Stem Cells Without Reprogramming Pluripotent Factors: a Novel Strategy in Stem Cell-Based Therapy for Tissue …

JJ Alloysius - ijcsejournal.org
Stem cells hold great promise for tissue regeneration and have the potential to treat many
incurable degenerative diseases. Cancer stem cells (CSCs), or cancer initiating cells, have …