Chronic ocular surface pain (COSP) may be defined as a feeling of pain, perceived as
originating from the ocular surface, that persists for> 3 months. COSP is a complex …

Introduction Dysfunction at various levels of the somatosensory system can lead to ocular
surface pain with a neuropathic component. Compared to nociceptive pain (due to noxious …

Background: Dysfunction at the ocular system via nociceptive or neuropathic mechanisms
can lead to chronic ocular pain. While many studies have reported on responses to …

Purpose To determine the prevalence, clinical characteristics, and risk factors associated
with neurotrophic keratopathy (NK) in patients with chronic ocular graft-versus-host disease …

Purpose To conduct a genome-wide association study (GWAS) of individuals with
neuropathic ocular pain (NOP) symptoms to identify genomic variants that may predispose …

Ocular surface itch and pain: key differences and similariti... : Current Opinion in Allergy and
Clinical Immunology Ocular surface itch and pain: key differences and similarities between the …

Dry eye and migraine are common diseases with large societal and economic burdens that
have recently been associated in the literature. This review outlines the link between dry eye …

The altered activity generated by corneal neuronal injury can result in morphological and
physiological changes in the architecture of synaptic connections in the nervous system …

Purpose Neurotrophic keratopathy (NK) is a degenerative disorder of the cornea
characterized by decreased sensory innervation, epitheliopathy, and impaired epithelial …

Several etiologies can contribute to ocular surface pain including nociceptive, peripheral
neuropathic, and central neuropathic mechanisms. Clinical clues can help identify …