Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Hypoxia and hemorheological properties in older individuals

A Raberin, J Burtscher, P Connes, GP Millet - Ageing Research Reviews, 2022 - Elsevier
Hypoxia is caused by insufficient oxygen availability for the organism leading to reduced
oxygen delivery to tissues and cells. It has been regarded as a severe threat to human …

Classification of red cell dynamics with convolutional and recurrent neural networks: a sickle cell disease case study

M Darrin, A Samudre, M Sahun, S Atwell, C Badens… - Scientific Reports, 2023 - nature.com
The fraction of red blood cells adopting a specific motion under low shear flow is a promising
inexpensive marker for monitoring the clinical status of patients with sickle cell disease. Its …

Effect of cell age and membrane rigidity on red blood cell shape in capillary flow

M Nouaman, A Darras, T John, G Simionato, MAE Rab… - Cells, 2023 - mdpi.com
Blood flow in the microcirculatory system is crucially affected by intrinsic red blood cell
(RBC) properties, such as their deformability. In the smallest vessels of this network, RBCs …

Morphometry and stiffness of red blood cells—signatures of neurodegenerative diseases and aging

V Strijkova-Kenderova, S Todinova… - International journal of …, 2021 - mdpi.com
Human red blood cells (RBCs) are unique cells with the remarkable ability to deform, which
is crucial for their oxygen transport function, and which can be significantly altered under …

Microfluidic viscometer using capillary pressure sensing

YJ Kang - Physics of Fluids, 2023 - pubs.aip.org
Blood viscosity is considered as a vital determinant of the efficiency of blood flow in blood-
vessel networks. The coflowing method is considered as a promising technique for …

Morphometric and nanomechanical screening of peripheral blood cells with atomic force microscopy for label-free assessment of Alzheimer's disease, Parkinson's …

SG Taneva, S Todinova, T Andreeva - International Journal of Molecular …, 2023 - mdpi.com
Neurodegenerative disorders (NDDs) are complex, multifactorial disorders with significant
social and economic impact in today's society. NDDs are predicted to become the second …

Microfluidic characterization of red blood cells microcirculation under oxidative stress

NA Besedina, EA Skverchinskaya, AS Ivanov… - Cells, 2021 - mdpi.com
Microcirculation is one of the basic functional processes where the main gas exchange
between red blood cells (RBCs) and surrounding tissues occurs. It is greatly influenced by …

Simple Assessment of Red Blood Cell Deformability using blood pressure in Capillary channels for effective detection of subpopulations in Red Blood cells

YJ Kang, S Serhrouchni, A Makhro, A Bogdanova… - ACS …, 2022 - ACS Publications
Assessment of red blood cell (RBC) deformability as a biomarker requires expensive
equipment to induce and monitor deformation. In this study, we present a simple method for …

Classification of Red Blood Cells Using Time-Distributed Convolutional Neural Networks from Simulated Videos

S Molčan, M Smiešková, H Bachratý, K Bachratá… - Applied Sciences, 2023 - mdpi.com
The elasticity of red blood cells (RBCs) plays a vital role in their efficient movement through
blood vessels, facilitating the transportation of oxygen within the bloodstream. However …