[HTML][HTML] Thiosemicarbazone derivatives of transition metals as multi-target drugs: a review

S Gupta, N Singh, T Khan, S Joshi - Results in Chemistry, 2022 - Elsevier
The mutations of bacteria and viruses along with the resistance of various targets to the
existing drugs have emerged as great challenges in the medical field. This imposes the …

Updates on drug designing approach through computational strategies: a review

I Azad, T Khan, N Ahmad, AR Khan, Y Akhter - Future Science OA, 2023 - Taylor & Francis
The drug discovery and development (DDD) process in pursuit of novel drug candidates is a
challenging procedure requiring lots of time and resources. Therefore, computer-aided drug …

Comparison of cytotoxicity evaluation of anticancer drugs between real-time cell analysis and CCK-8 method

L Cai, X Qin, Z Xu, Y Song, H Jiang, Y Wu, H Ruan… - ACS …, 2019 - ACS Publications
Critical cytotoxicity evaluation of pharmaceuticals is necessary for the clinical practice of
chemotherapy. To quantitatively evaluate cell viability, currently there are two main types of …

Tailoring of some novel bis-hydrazone metal chelates, spectral based characterization and DFT calculations for pharmaceutical applications and in-silico treatments …

HA Qasem, MR Aouad, HA Al-Abdulkarim… - Journal of Molecular …, 2022 - Elsevier
A series of new bis-hydrazone complexes was obtained from ((N'E, N'''E)-2, 2′-(1, 3-
phenylenebis (oxy)) bis (N'-(4, 5-di-tert-butyl-2-hydroxybenzylidene) acetohydrazide)) ligand …

Design, structural inspection of new bis (1H-benzo [d] imidazol-2-yl) methanone complexes: biomedical applications and theoretical implementations via DFT and …

FS Aljohani, OA Omran, EA Ahmed, ES Al-Farraj… - Inorganic Chemistry …, 2023 - Elsevier
In the present study, a novel bis (1H-benzo [d] imidazol-2-yl) methanone (H 2 L) ligand
derived from the interaction of 1, 2-phenylenediamine with diethyl 2-bromomalonate and its …

Novel isatin-based complexes of Mn (II) and Cu (II) ions: characterization, homogeneous catalysts for sulfides oxidation, bioactivity screening and theoretical …

MSS Adam, MM Makhlouf, A Alharbi… - Journal of Molecular …, 2022 - Elsevier
Two mononuclear manganese (II) and copper (II) complexes were prepared from the
coordination of 3, 5-di-tert-butyl isatin hydrazone derivative (HLOEt) with either 2: 1 or 1: 1 M …

Virtual screening of phytoconstituents from miracle herb nigella sativa targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 …

S Siddiqui, S Upadhyay, R Ahmad… - Journal of …, 2022 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel etiological agent
of coronavirus disease 2019 (COVID-19). Nigella sativa, commonly known as black seed or …

[HTML][HTML] Insights into the cytotoxicity and irritant potential of chlorhexidine digluconate: an in vitro and in ovo safety screening

S Dinu, A Matichescu, R Buzatu, I Marcovici… - Dentistry Journal, 2024 - mdpi.com
Chlorhexidine (CHX) represents one of the most commonly used antiseptics in dentistry and
other medical–pharmaceutical fields due to its broad-spectrum antimicrobial activity …

Synthesis, crystal structure, computational study and anti-virus effect of mixed ligand copper (II) complex with ONS donor Schiff base and 1, 10-phenanthroline

B Mohan, M Choudhary - Journal of Molecular Structure, 2021 - Elsevier
This work deals with the synthesis, crystal structure, computational study and antiviral
potential of mixed ligand copper (II) complex [Cu (L)(phen)](1),(where, H 2 L=(Z)-N'-((E)-2 …

Exploring nature's bounty: identification of Withania somnifera as a promising source of therapeutic agents against COVID-19 by virtual screening and in silico …

A Srivastava, S Siddiqui, R Ahmad… - Journal of …, 2022 - Taylor & Francis
Coronaviruses are etiological agents of extreme human and animal infection resulting in
abnormalities primarily in the respiratory tract. Presently, there is no defined COVID-19 …