[HTML][HTML] Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment

RF White, L Steele, JP O'Callaghan, K Sullivan… - Cortex, 2016 - Elsevier
Abstract Veterans of Operation Desert Storm/Desert Shield− the 1991 Gulf War (GW)− are a
unique population who returned from theater with multiple health complaints and disorders …

Pesticides, cognitive functions and dementia: A review

AM Aloizou, V Siokas, C Vogiatzi, E Peristeri… - Toxicology letters, 2020 - Elsevier
Pesticides are widely-used chemicals commonly applied in agriculture for the protection of
crops from pests. Depending on the class of pesticides, the specific substances may have a …

Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway …

LN Madhu, M Kodali, S Attaluri, B Shuai, L Melissari… - Redox Biology, 2021 - Elsevier
Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted
with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for …

Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation

F Alhasson, S Das, R Seth, D Dattaroy… - PloS one, 2017 - journals.plos.org
Many of the symptoms of Gulf War Illness (GWI) that include neurological abnormalities,
neuroinflammation, chronic fatigue and gastrointestinal disturbances have been traced to …

Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus

VK Parihar, B Hattiangady, B Shuai… - …, 2013 - nature.com
Impairments in mood and cognitive function are the key brain abnormalities observed in Gulf
war illness (GWI), a chronic multisymptom health problem afflicting∼ 25% of veterans who …

Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness

JP O'Callaghan, KA Kelly, AR Locker… - Journal of …, 2015 - Wiley Online Library
Abstract Gulf War Illness (GWI) is a multi‐symptom disorder with features characteristic of
persistent sickness behavior. Among conditions encountered in the Gulf War (GW) theater …

Gulf War illness: mechanisms underlying brain dysfunction and promising therapeutic strategies

B Dickey, LN Madhu, AK Shetty - Pharmacology & therapeutics, 2021 - Elsevier
Abstract Gulf War Illness (GWI), a chronic multisymptom health problem, afflicts~ 30% of
veterans served in the first GW. Impaired brain function is among the most significant …

Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness

B Hattiangady, V Mishra, M Kodali, B Shuai… - Frontiers in behavioral …, 2014 - frontiersin.org
Memory and mood deficits are the enduring brain-related symptoms in Gulf War illness
(GWI). Both animal model and epidemiological investigations have indicated that these …

Curcumin treatment leads to better cognitive and mood function in a model of Gulf War Illness with enhanced neurogenesis, and alleviation of inflammation and …

M Kodali, B Hattiangady, GA Shetty, A Bates… - Brain, behavior, and …, 2018 - Elsevier
Diminished cognitive and mood function are among the most conspicuous symptoms of Gulf
War Illness (GWI). Our previous studies in a rat model of GWI have demonstrated that …

Chronic oxidative stress, mitochondrial dysfunction, Nrf2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative …

GA Shetty, B Hattiangady, D Upadhya… - Frontiers in molecular …, 2017 - frontiersin.org
Memory and mood dysfunction are the key symptoms of Gulf war illness (GWI), a lingering
multi-symptom ailment afflicting> 200,000 veterans who served in the Persian Gulf War-1 …