Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions
This review highlights the importance of the biocatalyst, Candida parapsilosis for oxidation
and reduction reactions of organic compounds and establishes its versatility to generate a …
and reduction reactions of organic compounds and establishes its versatility to generate a …
Dehydrogenases/reductases for the synthesis of chiral pharmaceutical intermediates
Y Huang, N Liu, X Wu, Y Chen - Current Organic Chemistry, 2010 - ingentaconnect.com
The increasing trend of chiral drugs in the pharmaceutical industry has promoted greatly on
the development of numerous biocatalytic routes in combination with chemical methods …
the development of numerous biocatalytic routes in combination with chemical methods …
Chemoenzymatic Preparation of Enantiomerically Enriched (R)‐(–)‐Mandelic Acid Derivatives: Application in the Synthesis of the Active Agent Pemoline
M Poterała, M Dranka… - European Journal of …, 2017 - Wiley Online Library
The enantioselective resolution of several racemic derivatives of mandelic acid methyl ester
catalyzed by lipases from Pseudomonas fluorescens (Amano AK) or Burkholderia cepacia …
catalyzed by lipases from Pseudomonas fluorescens (Amano AK) or Burkholderia cepacia …
Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate
ZY You, ZQ Liu, YG Zheng - Applied microbiology and biotechnology, 2014 - Springer
Abstract Ethyl (R)-4-cyano-3-hydroxybutanoate (HN) is an important chiral synthon for side
chain of the cholesterol-lowering drug atorvastatin (Lipitor), which is the …
chain of the cholesterol-lowering drug atorvastatin (Lipitor), which is the …
Biocatalytic synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate with Candida krusei SW2026: a practical process for high enantiopurity and product titer
W Zhang, Y Ni, Z Sun, P Zheng, W Lin, P Zhu, N Ju - Process Biochemistry, 2009 - Elsevier
Ethyl (R)-2-hydroxy-4-phenylbutyrate ((R)-HPBE), a key intermediate in the production of
angiotensin-converting enzyme (ACE) inhibitors, was prepared by the microbial reduction of …
angiotensin-converting enzyme (ACE) inhibitors, was prepared by the microbial reduction of …
Enantio-and chemoselective Brønsted-acid/Mg (n Bu) 2 catalysed reduction of α-keto esters with catecholborane
D Enders, BA Stöckel, A Rembiak - Chemical Communications, 2014 - pubs.rsc.org
The first enantio-and chemoselective Brønsted-acid catalysed reduction of α-keto esters with
catecholborane has been developed. The α-hydroxy esters were obtained under mild …
catecholborane has been developed. The α-hydroxy esters were obtained under mild …
Yeast-mediated stereoselective reduction of α-acetylbutyrolactone
W Mączka, K Wińska, M Grabarczyk, B Żarowska - Applied Sciences, 2018 - mdpi.com
α'-1'-Hydroxyethyl-γ-butyrolactone—a product of reduction of α-acetylbutyrolactone
possesses two stereogenic centres and two reactive functionalities (an alcohol and an ester …
possesses two stereogenic centres and two reactive functionalities (an alcohol and an ester …
Enantioselective hydrolysis of racemic 1-phenylethyl acetate by an enzymatic system from fresh vegetables
A Vandenberghe, IE Markó, F Lucaccioni… - Industrial Crops and …, 2013 - Elsevier
High valuable enantiomerically pure compounds are potential chiral building blocks for the
synthesis of pharmaceutically important molecules, agrochemicals, flavors and asymmetric …
synthesis of pharmaceutically important molecules, agrochemicals, flavors and asymmetric …
Studies on the chemoenzymatic synthesis of (R)-and (S)-methyl 3-aryl-3-hydroxypropionates: the influence of toluene-pretreatment of lipase preparations on …
P Borowiecki, M Bretner - Tetrahedron: Asymmetry, 2013 - Elsevier
Two series (para-and meta-substituted) of racemic methyl esters of 3-aryl-3-
hydroxypropionic acid were prepared after which the enantiomers were separated by an …
hydroxypropionic acid were prepared after which the enantiomers were separated by an …
Integration of newly isolated biocatalyst and resin-based in situ product removal technique for the asymmetric synthesis of (R)-methyl mandelate
JL Guo, XQ Mu, Y Xu - Bioprocess and biosystems engineering, 2010 - Springer
The enantioselective reduction of methyl benzoylformate to (R)-methyl mandelate, an
important pharmaceutical intermediate and a versatile resolving agent, was investigated in …
important pharmaceutical intermediate and a versatile resolving agent, was investigated in …