WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …

Autism spectrum disorders (ASD) are common, complex and heterogeneous
neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD …

Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Abstract CD133 (prominin-1), a pentaspan membrane glycoprotein, is one of the most well-
characterized biomarkers used for the isolation of cancer stem cells (CSCs). The presence …

One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

The mechanism by which adult neural stem cells (NSCs) are established during
development is unclear. In this study, analysis of cell cycle progression by examining …

The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

Astrocytes are the most abundant cell type in the mammalian brain. Interest in astrocyte
function has increased dramatically in recent years because of their newly discovered roles …

Summary The Disrupted in Schizophrenia 1 (DISC1) gene is disrupted by a balanced
chromosomal translocation (1; 11)(q42; q14. 3) in a Scottish family with a high incidence of …