Branched chain amino acids: beyond nutrition metabolism

C Nie, T He, W Zhang, G Zhang, X Ma - International journal of molecular …, 2018 - mdpi.com
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …

Novel metabolic and physiological functions of branched chain amino acids: a review

S Zhang, X Zeng, M Ren, X Mao, S Qiao - Journal of animal science and …, 2017 - Springer
It is widely known that branched chain amino acids (BCAA) are not only elementary
components for building muscle tissue but also participate in increasing protein synthesis in …

[HTML][HTML] Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense

MM Leiva-Juárez, JK Kolls, SE Evans - Mucosal immunology, 2018 - Elsevier
Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …

Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

β-Defensins: farming the microbiome for homeostasis and health

KG Meade, C O'Farrelly - Frontiers in Immunology, 2019 - frontiersin.org
Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?

YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

Recent progress on branched-chain amino acids in obesity, diabetes, and beyond

MAB Siddik, AC Shin - Endocrinology and Metabolism, 2019 - synapse.koreamed.org
Branched-chain amino acids (BCAAs) are essential amino acids that are not synthesized in
our body; thus, they need to be obtained from food. They have shown to provide many …

A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer

PA Vieyra-Garcia, P Wolf - Pharmacology & therapeutics, 2021 - Elsevier
UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …

Host defense peptides in nutrition and diseases: a contributor of immunology modulation

X Dou, D Yan, S Liu, N Gao, Z Ma, Z Shi… - Journal of Agricultural …, 2023 - ACS Publications
Host defense peptides (HDPs) are primary components of the innate immune system with
diverse biological functions, such as antibacterial ability and immunomodulatory function …

Isoleucine plays an important role for maintaining immune function

C Gu, X Mao, D Chen, B Yu… - Current Protein and …, 2019 - ingentaconnect.com
Branched chain amino acids are the essential nutrients for humans and many animals. As
functional amino acids, they play important roles in physiological functions, including …