Advanced maturation of human cardiac tissue grown from pluripotent stem cells

K Ronaldson-Bouchard, SP Ma, K Yeager, T Chen… - Nature, 2018 - nature.com
Cardiac tissues generated from human induced pluripotent stem cells (iPSCs) can serve as
platforms for patient-specific studies of physiology and disease,,,,–. However, the predictive …

Subcellular connectomic analyses of energy networks in striated muscle

CKE Bleck, Y Kim, TB Willingham, B Glancy - Nature communications, 2018 - nature.com
Mapping biological circuit connectivity has revolutionized our understanding of structure-
function relationships. Although connectomic analyses have primarily focused on neural …

[HTML][HTML] Electron tomography of rabbit cardiomyocyte three-dimensional ultrastructure

EA Rog-Zielinska, CM Johnston, ET O'Toole… - Progress in biophysics …, 2016 - Elsevier
The field of cardiovascular research has benefitted from rapid developments in imaging
technology over the last few decades. Accordingly, an ever growing number of large …

Sheet-like remodeling of the transverse tubular system in human heart failure impairs excitation-contraction coupling and functional recovery by mechanical unloading

T Seidel, S Navankasattusas, A Ahmad, NA Diakos… - Circulation, 2017 - Am Heart Assoc
Background: Cardiac recovery in response to mechanical unloading by left ventricular assist
devices (LVADs) has been demonstrated in subgroups of patients with chronic heart failure …

Postnatal cardiovascular adaptation

AW Gill - Archives of Disease in Childhood-Fetal and Neonatal …, 2019 - fn.bmj.com
The heart undergoes rapid transformations in function during the transition to extrauterine
life. Our understanding of the adaptive physiology underlying this process is able to inform …

[图书][B] Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy

Y Vassilevski, M Olshanskii, S Simakov, A Kolobov… - 2020 - books.google.com
Personalized Computational Hemodynamics: Models, Methods, and Applications for
Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the …

Technical advances in studying cardiac electrophysiology–role of rabbit models

C Kang, JA Brennan, S Kuzmiak-Glancy… - Progress in Biophysics …, 2016 - Elsevier
Cardiovascular research has made a major contribution to an unprecedented 10 year
increase in life expectancy during the last 50 years: most of this increase due to a decline in …

Solute movement in the t-tubule system of rabbit and mouse cardiomyocytes

CHT Kong, EA Rog-Zielinska, P Kohl… - Proceedings of the …, 2018 - National Acad Sciences
Cardiac transverse (t-) tubules carry both electrical excitation and solutes toward the cell
center but their ability to transport small molecules is unclear. While fluorescence recovery …

Author Correction: Advanced maturation of human cardiac tissue grown from pluripotent stem cells

K Ronaldson-Bouchard, SP Ma, K Yeager, T Chen… - Nature, 2019 - nature.com
In this Letter, there are several errors to the following figures. In Fig. 2e, the y-axis labels
should have been '0, 50, 100, 150, 200, 250 and 300'rather than '0, 50, 100, 100, 200, 200 …

Arrhythmogenic and metabolic remodelling of failing human heart

CR Gloschat, AC Koppel, KK Aras… - The Journal of …, 2016 - Wiley Online Library
Heart failure (HF) is a major cause of morbidity and mortality worldwide. The global burden
of HF continues to rise, with prevalence rates estimated at 1–2% and incidence approaching …