Circadian oscillators: around the transcription–translation feedback loop and on to output

JM Hurley, JJ Loros, JC Dunlap - Trends in biochemical sciences, 2016 - cell.com
From cyanobacteria to mammals, organisms have evolved timing mechanisms to adapt to
environmental changes in order to optimize survival and improve fitness. To anticipate these …

The circadian clock of Neurospora crassa

CL Baker, JJ Loros, JC Dunlap - FEMS microbiology reviews, 2012 - academic.oup.com
Circadian clocks organize our inner physiology with respect to the external world, providing
life with the ability to anticipate and thereby better prepare for major fluctuations in its …

CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

Y Isojima, M Nakajima, H Ukai… - Proceedings of the …, 2009 - National Acad Sciences
A striking feature of the circadian clock is its flexible yet robust response to various
environmental conditions. To analyze the biochemical processes underlying this flexible-yet …

Making time: conservation of biological clocks from fungi to animals

JC Dunlap, JJ Loros - Microbiology spectrum, 2017 - Am Soc Microbiol
The capacity for biological timekeeping arose at least three times through evolution, in
prokaryotic cyanobacteria, in cells that evolved into higher plants, and within the group of …

Thermal adaptation and plasticity of the plant circadian clock

KE Gil, CM Park - New Phytologist, 2019 - Wiley Online Library
Contents Summary 1215 I. Introduction 1215 II. Molecular organization of the plant circadian
clock 1216 III. Temperature compensation 1219 IV. Temperature regulation of circadian …

CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop

Q He, J Cha, Q He, HC Lee, Y Yang… - Genes & …, 2006 - genesdev.cshlp.org
The eukaryotic circadian oscillators consist of circadian negative feedback loops. In
Neurospora, it was proposed that the FREQUENCY (FRQ) protein promotes the …

The Role of the Arabidopsis Morning Loop Components CCA1, LHY, PRR7, and PRR9 in Temperature Compensation

PA Salomé, D Weigel, CR McClung - The Plant Cell, 2010 - academic.oup.com
A defining, yet poorly understood characteristic of the circadian clock is that it is buffered
against changes in temperature such that the period length is relatively constant across a …

Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock

CL Baker, AN Kettenbach, JJ Loros, SA Gerber… - Molecular cell, 2009 - cell.com
Circadian systems are comprised of multiple proteins functioning together to produce
feedback loops driving robust, approximately 24 hr rhythms. In all circadian systems …

Decoupling circadian clock protein turnover from circadian period determination

LF Larrondo, C Olivares-Yañez, CL Baker, JJ Loros… - Science, 2015 - science.org
INTRODUCTION Circadian oscillators allow individual organisms to coordinate metabolism
with day/night cycles and to anticipate such changes. Such oscillators in fungi and animals …

Temperature and nitrogen effects on regulators and products of the flavonoid pathway: experimental and kinetic model studies

KM Olsen, R Slimestad, US Lea, C Brede… - Plant, Cell & …, 2009 - Wiley Online Library
The flavonoid pathway is known to be up‐regulated by different environmental stress factors.
Down‐regulation of the pathway is much less studied and is emphasized in the present …