Abstract The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate PGx
implementation by developing evidence-based pharmacogenetics guidelines to optimize …

Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Abstract The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate
pharmacogenetics implementation in clinical practice by developing evidence-based …

Abstract The Dutch Pharmacogenetics Working Group (DPWG) guideline presented here,
presents the gene-drug interaction between the genes CYP2C19 and CYP2D6 and …

Pharmacogenomics (PGx) is an integral part of precision medicine and contributes to the
maximization of drug efficacy and reduction of adverse drug event risk. Accurate information …

Abstract The Dutch Pharmacogenetics Working Group (DPWG) aims to facilitate PGx
implementation by developing evidence-based pharmacogenetics guidelines to optimize …

Pharmacogenomics (PGx), examining the effect of genetic variation on interpatient variation
in drug disposition and response, has been widely studied for several decades. However, as …

Over 20% of US Food and Drug Administration (FDA)‐approved drugs in the United States
are metabolized by the hepatic enzyme cytochrome P450 2D6 (CYP2D6). The gene …

Pharmacogenetics (PGx) studies the effect of heritable genetic variation on drug response.
Clinical adoption of PGx has remained limited, despite progress in the field. To promote …

Patients suffering from chronic pain may respond differently to analgesic medications. For
some, pain relief is insufficient, while others experience side effects. Although …