Brain Iron Accumulation in Atypical Parkinsonian Syndromes: in vivo MRI Evidences for Distinctive Patterns

JH Lee, MS Lee - Frontiers in Neurology, 2019 - frontiersin.org
Recent data suggest mechanistic links among perturbed iron homeostasis, oxidative stress,
and misfolded protein aggregation in neurodegenerative diseases. Iron overload and …

Role of endolysosome function in iron metabolism and brain carcinogenesis

PW Halcrow, ML Lynch, JD Geiger, JE Ohm - Seminars in cancer biology, 2021 - Elsevier
Iron, the most abundant metal in human brain, is an essential microelement that regulates
numerous cellular mechanisms. Some key physiological roles of iron include oxidative …

Investigation of deep-learning-driven identification of multiple sclerosis patients based on susceptibility-weighted images using relevance analysis

A Lopatina, S Ropele, R Sibgatulin… - Frontiers in …, 2020 - frontiersin.org
The diagnosis of multiple sclerosis (MS) is usually based on clinical symptoms and signs of
damage to the central nervous system, which is assessed using magnetic resonance …

Regional high iron in the substantia nigra differentiates Parkinson's disease patients from healthy controls

K Ghassaban, N He, SK Sethi, P Huang… - Frontiers in aging …, 2019 - frontiersin.org
Background: Iron is important in the pathophysiology of Parkinson's disease (PD)
specifically related to degeneration of the substantia nigra (SN). Magnetic resonance …

Iron content in deep gray matter as a function of age using quantitative susceptibility mapping: a multicenter study

Y Li, SK Sethi, C Zhang, Y Miao… - Frontiers in …, 2021 - frontiersin.org
Purpose To evaluate the effect of resolution on iron content using quantitative susceptibility
mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in …

[HTML][HTML] Quantitative susceptibility mapping based hybrid feature extraction for diagnosis of Parkinson's disease

B Xiao, N He, Q Wang, Z Cheng, Y Jiao, EM Haacke… - NeuroImage: Clinical, 2019 - Elsevier
Parkinson's disease is the second most common neurodegenerative disease in the elderly
after Alzheimer's disease. The aetiology and pathogenesis of Parkinson's disease (PD) are …

Quantitative evaluation of brain iron accumulation in different stages of Parkinson's disease

KR Li, J Avecillas‐Chasin, TD Nguyen… - Journal of …, 2022 - Wiley Online Library
Abstract Background and Purpose Excessive brain iron deposition is involved in Parkinson's
disease (PD) pathogenesis. However, the correlation of iron accumulation in various brain …

[HTML][HTML] Topics on quantitative liver magnetic resonance imaging

YXJ Wáng, X Wang, P Wu, Y Wang… - … imaging in medicine …, 2019 - ncbi.nlm.nih.gov
Liver magnetic resonance imaging (MRI) is subject to continuous technical innovations
through advances in hardware, sequence and novel contrast agent development. In order to …

Quantitative susceptibility mapping shows lower brain iron content in children with autism

S Tang, Y Xu, X Liu, Z Chen, Y Zhou, L Nie, L He - European Radiology, 2021 - Springer
Objective To explore the application of quantitative susceptibility mapping (QSM) of brain
iron content in children with autism. Methods For the control group, 40 normal children aged …

[HTML][HTML] Iron Deficiency and Sleep/Wake Behaviors: A Scoping Review of Clinical Practice Guidelines—How to Overcome the Current Conundrum?

S McWilliams, O Hill, OS Ipsiroglu, S Clemens… - Nutrients, 2024 - mdpi.com
Current evidence suggests that iron deficiency (ID) plays a key role in the pathogenesis of
conditions presenting with restlessness such as attention deficit hyperactivity disorder …