[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H Jin, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation

Z Yang, F Xu, AE Teschendorff, Y Zhao… - Frontiers in molecular …, 2022 - frontiersin.org
DNA methylation is one of the most important epigenetic mechanisms that governing
regulation of gene expression, aberrant DNA methylation patterns are strongly associated …

Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction

G Jia, J Ping, X Guo, Y Yang, R Tao, B Li, S Ambs… - Nature …, 2024 - nature.com
We performed genome-wide association studies of breast cancer including 18,034 cases
and 22,104 controls of African ancestry. Genetic variants at 12 loci were associated with …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …

Association of the Plasma Long Non-coding RNA MEG3 With Parkinson's Disease

Y Quan, J Wang, S Wang, J Zhao - Frontiers in Neurology, 2020 - frontiersin.org
Objective: To investigate the expression level of the maternally expressed gene-3 (MEG3) of
the free long non-coding RNA (lncRNAs) in the plasma of Parkinson's disease (PD) patients …

Novel lncRNA PSMG3‑AS1 functions as a miR‑143‑3p sponge to increase the proliferation and migration of breast cancer cells

Y Cui, Y Fan, G Zhao, Q Zhang, Y Bao… - Oncology …, 2020 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are considered to be important regulators in breast
cancer. In the present study, the potential mechanisms and functional roles of lncRNA …

Long non‐coding RNAs differential expression in breast cancer subtypes: what do we know?

C Mathias, EP Zambalde, P Rask, DF Gradia… - Clinical …, 2019 - Wiley Online Library
Breast Cancer (BC) is the most commonly diagnosed cancer and is the leading cause of
cancer deaths in women. BC is a heterogeneous disease with different clinical and genetic …

Emerging roles and mechanisms of lncRNA FOXD3-AS1 in human diseases

Q Yao, X Zhang, D Chen - Frontiers in Oncology, 2022 - frontiersin.org
Numerous long noncoding RNAs (lncRNAs) have been identified as powerful regulators of
human diseases. The lncRNA FOXD3-AS1 is a novel lncRNA that was recently shown to …

Integrative analysis of the lncRNA-associated ceRNA network reveals lncRNAs as potential prognostic biomarkers in human muscle-invasive bladder cancer

L Lyu, W Xiang, JY Zhu, T Huang, JD Yuan… - Cancer management …, 2019 - Taylor & Francis
Background Long noncoding RNAs (lncRNAs) play important roles in competing
endogenous RNA (ceRNA) networks involved in the development and progression of …

[HTML][HTML] Long non-coding rna norad inhibits breast cancer cell proliferation and metastasis by regulating mir-155-5p/socs1 axis

W Liu, X Zhou, Y Li, H Jiang, A Chen - Journal of Breast Cancer, 2021 - ncbi.nlm.nih.gov
Purpose Non-coding RNA activated by DNA damage (NORAD) has been reported to be a
cancer-related long non-coding RNA (lncRNA) implicated in the progression of several …