Neuromodulation by the immune system: a focus on cytokines
Interactions between the immune system and the nervous system have been described
mostly in the context of diseases. More recent studies have begun to reveal how certain …
mostly in the context of diseases. More recent studies have begun to reveal how certain …
[HTML][HTML] The meningeal lymphatic system: a new player in neurophysiology
The nature of fluid dynamics within the brain parenchyma is a focus of intensive research. Of
particular relevance is its participation in diseases associated with protein accumulation and …
particular relevance is its participation in diseases associated with protein accumulation and …
[HTML][HTML] Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …
Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons
Abstract Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate
immune system and widely studied in contexts of infection and autoimmunity. Studies …
immune system and widely studied in contexts of infection and autoimmunity. Studies …
Social anxiety disorder-associated gut microbiota increases social fear
NL Ritz, M Brocka, MI Butler… - Proceedings of the …, 2024 - National Acad Sciences
Social anxiety disorder (SAD) is a crippling psychiatric disorder characterized by intense
fear or anxiety in social situations and their avoidance. However, the underlying biology of …
fear or anxiety in social situations and their avoidance. However, the underlying biology of …
Meningeal immunity and its function in maintenance of the central nervous system in health and disease
K Alves de Lima, J Rustenhoven… - Annual review of …, 2020 - annualreviews.org
Neuroimmunology, albeit a relatively established discipline, has recently sparked numerous
exciting findings on microglia, the resident macrophages of the central nervous system …
exciting findings on microglia, the resident macrophages of the central nervous system …
A metabolite-triggered tuft cell-ILC2 circuit drives small intestinal remodeling
C Schneider, CE O'Leary, J von Moltke, HE Liang… - Cell, 2018 - cell.com
The small intestinal tuft cell-ILC2 circuit mediates epithelial responses to intestinal helminths
and protists by tuft cell chemosensory-like sensing and IL-25-mediated activation of lamina …
and protists by tuft cell chemosensory-like sensing and IL-25-mediated activation of lamina …
Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory
M Ribeiro, HC Brigas, M Temido-Ferreira… - Science …, 2019 - science.org
The notion of “immune privilege” of the brain has been revised to accommodate its
infiltration, at steady state, by immune cells that participate in normal neurophysiology …
infiltration, at steady state, by immune cells that participate in normal neurophysiology …
IL-17a promotes sociability in mouse models of neurodevelopmental disorders
A subset of children with autism spectrum disorder appear to show an improvement in their
behavioural symptoms during the course of a fever, a sign of systemic inflammation,. Here …
behavioural symptoms during the course of a fever, a sign of systemic inflammation,. Here …
IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease
Neuroinflammation in patients with Alzheimer's disease (AD) and related mouse models has
been recognized for decades, but the contribution of the recently described meningeal …
been recognized for decades, but the contribution of the recently described meningeal …