Medium spiny neurons (MSNs) constitute the vast majority of striatal neurons and the
principal interface between dopamine reward signals and functionally diverse cortico-basal …

The commonalities and differences in cell-type-specific pathways that lead to Alzheimer
disease (AD) and Parkinson disease (PD) remain unknown. Here, we performed a single …

Deciphering the striatal interneuron diversity is key to understanding the basal ganglia
circuit and to untangling the complex neurological and psychiatric diseases affecting this …

Prior efforts to image cholinergic projections in human brain in vivo had significant technical
limitations. We used the vesicular acetylcholine transporter (VAChT) ligand [18F] …

Aims The striatum is mainly composed of projection neurons. It also contains interneurons,
which modulate and control striatal output. The aim of the present study was to assess the …

Synapses are fundamental to the function of the central nervous system and are implicated
in a number of brain disorders. Despite their pivotal role, a comprehensive imaging resource …

Lipid peroxidation is one of the primary events of the cell injury process. In
pathophysiological condition, it is undergoing the initiation of organ damage. Various free …

Background The (neo) striatum is the major input structure of the basal nuclei, which is
involved in the execution of voluntary movements, but also in controlling the processes that …

The dorsomedial striatum (DMS) is an associative node involved in the adaptation of
ongoing actions to the environmental context and in the initial formation of motor sequences …

Williams syndrome (WS) is a rare neurodevelopmental disorder caused by the hemideletion
of approximately 25–28 genes at 7q11. 23. Its unusual social and cognitive phenotype is …