Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres

J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

[PDF][PDF] Diagnosing diabetic neuropathy: something old, something new

IN Petropoulos, G Ponirakis, A Khan… - Diabetes & …, 2018 - synapse.koreamed.org
There are potentially many ways of assessing diabetic peripheral neuropathy (DPN).
However, they do not fulfill US Food and Drug Administration (FDA) requirements in relation …

An artificial intelligence-based deep learning algorithm for the diagnosis of diabetic neuropathy using corneal confocal microscopy: a development and validation …

BM Williams, D Borroni, R Liu, Y Zhao, J Zhang, J Lim… - Diabetologia, 2020 - Springer
Aims/hypothesis Corneal confocal microscopy is a rapid non-invasive ophthalmic imaging
technique that identifies peripheral and central neurodegenerative disease. Quantification of …

Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease

A Barros, J Queiruga-Piñeiro, J Lozano-Sanroma… - The Ocular Surface, 2022 - Elsevier
Purpose To describe the association between Sars-CoV-2 infection and small fiber
neuropathy in the cornea identified by in vivo corneal confocal microscopy. Methods Twenty …

Corneal confocal microscopy: ready for prime time

IN Petropoulos, G Ponirakis, A Khan… - Clinical and …, 2020 - Taylor & Francis
Corneal confocal microscopy is a non‐invasive ophthalmic imaging modality, which was
initially used for the diagnosis and management of corneal diseases. However, over the last …

[HTML][HTML] Corneal confocal microscopy: a biomarker for diabetic peripheral neuropathy

IN Petropoulos, G Ponirakis, M Ferdousi, S Azmi… - Clinical …, 2021 - Elsevier
Purpose Diagnosing early diabetic peripheral neuropathy remains a challenge due to
deficiencies in currently advocated end points. The cornea is densely innervated with small …

Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy

WZ So, NSQ Wong, HC Tan, MTY Lin… - Neural Regeneration …, 2022 - journals.lww.com
Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting
nerves in all parts of the body including corneal nerves and peripheral nervous system …

In vivo confocal microscopy morphometric analysis of corneal subbasal nerve plexus in dry eye disease using newly developed fully automated system

G Giannaccare, M Pellegrini, S Sebastiani… - Graefe's Archive for …, 2019 - Springer
Purpose To evaluate in vivo confocal microscopy (IVCM) features of corneal subbasal nerve
plexus (SNP) in the setting of dry eye disease (DED) using fully automated software …

Diabetic keratopathy: redox signaling pathways and therapeutic prospects

F Buonfiglio, J Wasielica-Poslednik, N Pfeiffer… - Antioxidants, 2024 - mdpi.com
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …

Relationships between activated dendritic cells and dry eye symptoms and signs

H Levine, J Hwang, H Dermer, D Mehra, W Feuer… - The ocular …, 2021 - Elsevier
Purpose To examine whether “activated” dendritic cells (aDCs) could serve as a biomarker
of systemic immune disorders in individuals with dry eye (DE) symptoms. Secondarily, to …