Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Isolates of Aspergillus species are able to produce a large number of secondary
metabolites. The profiles of biosynthetic families of secondary metabolites are species …

Abstract Background The fungal genus Aspergillus is of critical importance to humankind.
Species include those with industrial applications, important pathogens of humans, animals …

The hallmark trait of fungal secondary-metabolite gene clusters is well established,
consisting of contiguous enzymatic and often regulatory gene (s) devoted to the production …

Covering: 1936 to 2013 Epidithiodioxopiperazine alkaloids possess an astonishing array of
molecular architecture and generally exhibit potent biological activity. Nearly twenty distinct …

To stop the antimicrobial resistance crisis, there is an urgent need for increased investment
in antimicrobial research and development. Currently, many researchers are focussing on …

Four new diketopiperazines including spirobrocazines A–C (1–3) and brocazine G (4) were
characterized from the mangrove-derived Penicillium brocae MA-231. Compounds 1 and 2 …

Secondary metabolites (SMs) produced by filamentous fungi possess diverse bioactivities
that make them excellent drug candidates. Whole genome sequencing has revealed that …

Terrein is a fungal metabolite with ecological, antimicrobial, antiproliferative, and
antioxidative activities. Although it is produced by Aspergillus terreus as one of its major …

Actinomycetes and filamentous fungi produce a wide range of bioactive compounds, with
applications as antimicrobials, anticancer agents or agrochemicals. Their genomes contain …