[HTML][HTML] Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy

Y Jiang, L Rubin, T Peng, L Liu, X Xing… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
The COVID-19 outbreak is emerging as a significant public health challenge. Excessive
production of proinflammatory cytokines, also known as cytokine storm, is a severe clinical …

A COVID-19 vaccine: big strides come with big challenges

J Mellet, MS Pepper - Vaccines, 2021 - mdpi.com
As of 8 January 2021, there were 86,749,940 confirmed coronavirus disease 2019 (COVID-
19) cases and 1,890,342 COVID-19-related deaths worldwide, as reported by the World …

Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials

C Axfors, P Janiaud, AM Schmitt, J van't Hooft… - BMC infectious …, 2021 - Springer
Background Convalescent plasma has been widely used to treat COVID-19 and is under
investigation in numerous randomized clinical trials, but results are publicly available only …

Convalescent plasma associates with reduced mortality and improved clinical trajectory in patients hospitalized with COVID-19

SAA Egloff, A Junglen, JSA Restivo… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Evidence supporting convalescent plasma (CP), one of the first
investigational treatments for coronavirus disease 2019 (COVID-19), has been inconclusive …

Convalescent plasma (hyperimmune immunoglobulin) for COVID-19 management: An update

VP Chavda, R Bezbaruah, S Dolia, N Shah… - Process …, 2023 - Elsevier
The pandemic COVID-19 has spread widely throughout the globe and has been responsible
for millions of deaths worldwide. Recently, it has been identified that there is no specific and …

Convalescent plasma may be a possible treatment for COVID-19: A systematic review

Y Wang, P Huo, R Dai, X Lv, S Yuan, Y Zhang… - International …, 2021 - Elsevier
Introduction The coronavirus disease 2019 (COVID-19) pandemic has spread globally.
Therapeutic options including antivirals, anti-inflammatory compounds, and vaccines are still …

Hyperimmune anti-COVID-19 IVIG (C-IVIG) treatment in severe and critical COVID-19 patients: A phase I/II randomized control trial

S Ali, SM Uddin, E Shalim, MA Sayeed, F Anjum… - …, 2021 - thelancet.com
Abstract Background Hyperimmune anti-COVID-19 Intravenous Immunoglobulin (C-IVIG) is
an unexplored therapy amidst the rapidly evolving spectrum of medical therapies for COVID …

Insight into COVID-19's epidemiology, pathology, and treatment

A Aimrane, MA Laaradia, D Sereno, P Perrin, A Draoui… - Heliyon, 2022 - cell.com
The newly emerged 2019 coronavirus disease (COVID-19) has urged scientific and medical
communities to focus on epidemiology, pathophysiology, and treatment of SARS-CoV-2 …

Convalescent plasma for patients with severe coronavirus disease 2019 (COVID-19): a matched cohort study

R Rogers, F Shehadeh, EK Mylona… - Clinical Infectious …, 2021 - academic.oup.com
Background The efficacy of convalescent plasma (CP) for the treatment of coronavirus
disease 2019 (COVID-19) remains unclear. Methods In a matched cohort analysis of …

Central nervous system outcomes of COVID-19

MF Doyle - Translational Research, 2022 - Elsevier
The worldwide pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has infected an estimated 200 million people with over 4 million deaths …