[HTML][HTML] Putative animal models of restless legs syndrome: A systematic review and evaluation of their face and construct validity

A Silvani, I Ghorayeb, M Manconi, Y Li, S Clemens - Neurotherapeutics, 2023 - Elsevier
Restless legs syndrome (RLS) is a sensorimotor disorder that severely affects sleep. It is
characterized by an urge to move the legs, which is often accompanied by periodic limb …

Longitudinal manganese‐enhanced magnetic resonance imaging of neural projections and activity

TW Uselman, CS Medina, HB Gray… - NMR in …, 2022 - Wiley Online Library
Manganese‐enhanced magnetic resonance imaging (MEMRI) holds exceptional promise
for preclinical studies of brain‐wide physiology in awake‐behaving animals. The objectives …

Single-prolonged stress impairs prefrontal cortex control of amygdala and striatum in rats

VM Piggott, KE Bosse, MJ Lisieski… - Frontiers in Behavioral …, 2019 - frontiersin.org
Medial prefrontal cortex (mPFC), amygdala, and striatum neurocircuitry has been shown to
play an important role in post-traumatic stress disorder (PTSD) pathology in humans …

The role of BTBD9 in striatum and restless legs syndrome

S Lyu, H Xing, MP DeAndrade, Y Liu, PD Perez… - Eneuro, 2019 - eneuro.org
Restless legs syndrome (RLS) is a sensory-motor neurological disorder characterized by
uncomfortable sensations in the extremities, generally at night, which is often relieved by …

The role of BTBD9 in the cerebellum, sleep-like behaviors and the restless legs syndrome

S Lyu, H Xing, MP DeAndrade, PD Perez, F Yokoi… - Neuroscience, 2020 - Elsevier
Recent genome-wide association studies (GWAS) have found cerebellum as a top hit for
sleep regulation. Restless legs syndrome (RLS) is a sleep-related sensorimotor disorder …

Current and emerging neuromodulation therapies for addiction: insight from pre-clinical studies

M Creed - Current Opinion in Neurobiology, 2018 - Elsevier
Highlights•Clinical studies support the use of STN-DBS and NAc-DBS for treating
addiction.•Pre-clinical studies can inform DBS parameters by elucidating underlying …

Abdominal surgery plus sevoflurane exposure induces abnormal emotional changes and cognitive dysfunction in aged rats

JM Lv, LM Zhang, JX Wang, JJ Shao, XG Guo… - Behavioural Brain …, 2023 - Elsevier
Background Cognitive impairment, which includes perioperative psychological distress and
cognitive dysfunction, can be determined by preoperative and post-operative …

Sensitization-dependent nicotine place preference in the adult zebrafish

A Pisera-Fuster, L Rocco, MP Faillace… - Progress in Neuro …, 2019 - Elsevier
Sensitization of motor activity is a behavioural test to evaluate the effects of
psychostimulants. Conditioned place preference (CPP) is an associative learning procedure …

Striatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling

SH Song, WJ Jang, EY Jang, OH Kim, H Kim… - Frontiers in …, 2022 - frontiersin.org
MicroRNA (miRNA)-mediated striatal gene regulation may play an important role in
methamphetamine (METH) addiction. This study aimed to identify changes in novel miRNAs …

[HTML][HTML] Astrocytic regulation of cocaine locomotor sensitization in EcoHIV infected mice

Q Xie, R Dasari, MD Namba, LA Buck, CM Side… - …, 2025 - Elsevier
Cocaine use disorder (CUD) is highly comorbid with HIV infection and worsens HIV
outcomes. Preclinical research on the outcomes of HIV infection may yield crucial …