Ebola haemorrhagic fever

H Feldmann, TW Geisbert - The Lancet, 2011 - thelancet.com
Ebola viruses are the causative agents of a severe form of viral haemorrhagic fever in man,
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …

Pathogenicity and virulence of Marburg virus

MH Abir, T Rahman, A Das, SN Etu, IH Nafiz, A Rakib… - Virulence, 2022 - Taylor & Francis
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …

Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection

BR Amman, SA Carroll, ZD Reed, TK Sealy… - 2012 - journals.plos.org
Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease
in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based …

Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus

I Messaoudi, GK Amarasinghe, CF Basler - Nature Reviews …, 2015 - nature.com
Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …

Isolation of genetically diverse Marburg viruses from Egyptian fruit bats

JS Towner, BR Amman, TK Sealy, SAR Carroll… - PLoS …, 2009 - journals.plos.org
In July and September 2007, miners working in Kitaka Cave, Uganda, were diagnosed with
Marburg hemorrhagic fever. The likely source of infection in the cave was Egyptian fruit bats …

Filoviruses in bats: current knowledge and future directions

KJ Olival, DTS Hayman - Viruses, 2014 - mdpi.com
Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health
and species conservation by causing hemorrhagic fever outbreaks with high mortality rates …

Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach

SA Sami, KKS Marma, S Mahmud, MAN Khan… - ACS …, 2021 - ACS Publications
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …

Basic clinical and laboratory features of filoviral hemorrhagic fever

MG Kortepeter, DG Bausch… - The Journal of infectious …, 2011 - academic.oup.com
Abstract The filoviruses Marburg and Ebola cause severe hemorrhagic fever (HF) in
humans. Beginning with the 1967 Marburg outbreak, 30 epidemics, isolated cases, and …

Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in …

MJ Hamer, KV Houser, AR Hofstetter, AM Ortega-Villa… - The Lancet, 2023 - thelancet.com
Background WHO has identified Marburg virus as an emerging virus requiring urgent
vaccine research and development, particularly due to its recent emergence in Ghana. We …

Marburg virus infection detected in a common African bat

JS Towner, X Pourrut, CG Albariño, CN Nkogue… - PloS one, 2007 - journals.plos.org
Marburg and Ebola viruses can cause large hemorrhagic fever (HF) outbreaks with high
case fatality (80–90%) in human and great apes. Identification of the natural reservoir of …