Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

Z Zhou, J Song, L Nie, X Chen - Chemical society reviews, 2016 - pubs.rsc.org
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

Stimuli-responsive functional micro-/nanorobots: a review

Y Zhou, M Ye, C Hu, H Qian, BJ Nelson, X Wang - ACS nano, 2023 - ACS Publications
Stimuli-responsive functional micro-/nanorobots (srFM/Ns) are a class of intelligent, efficient,
and promising microrobots that can react to external stimuli (such as temperature, light …

Ultrasound-controllable engineered bacteria for cancer immunotherapy

MH Abedi, MS Yao, DR Mittelstein, A Bar-Zion… - Nature …, 2022 - nature.com
Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

Thermo-sensitive polymers in medicine: A review

P Zarrintaj, M Jouyandeh, MR Ganjali… - European Polymer …, 2019 - Elsevier
A wide variety of smart polymer systems such as thermosensitive polymers (TSPs) have
been developed and applied mimicking nature. TSPs are a class of macromolecules that …

Smart stimuli-responsive implantable drug delivery systems for programmed and on-demand cancer treatment: An overview on the emerging materials

Z Mazidi, S Javanmardi, SM Naghib… - Chemical Engineering …, 2022 - Elsevier
Despite noteworthy developments in tumor therapy, cancer is still one of the main reasons
for death worldwide. While present cures supply hopeful marks, they trigger harsh …

Overcoming the blood–brain barrier. challenges and tricks for CNS drug delivery

LA Bors, F Erdő - Scientia Pharmaceutica, 2019 - mdpi.com
Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …

Drug delivery by ultrasound-responsive nanocarriers for cancer treatment

K Entzian, A Aigner - Pharmaceutics, 2021 - mdpi.com
Conventional cancer chemotherapies often exhibit insufficient therapeutic outcomes and
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …

Stimuli-responsive nano-assemblies for remotely controlled drug delivery

F Li, Y Qin, J Lee, H Liao, N Wang, TP Davis… - Journal of Controlled …, 2020 - Elsevier
Stimuli-responsive nano-assemblies are emerging as promising drug delivery systems
(DDSs) with spatial and temporal tenability, which can undergo structural transition for …