Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline

T Anderson, S Sharma, MA Kelberman… - Journal of …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia. Obesity in middle age
increases AD risk and severity, which is alarming given that obesity prevalence peaks at …

[HTML][HTML] Early resource scarcity causes cortical astrocyte enlargement and sex-specific changes in the orbitofrontal cortex transcriptome in adult rats

C Deckers, R Karbalaei, NA Miles, EV Harder… - Neurobiology of …, 2024 - Elsevier
Astrocyte morphology affects function, including the regulation of glutamatergic signaling.
This morphology changes dynamically in response to the environment. However, how early …