Angiogenesis is an essential process in normal development and in adult physiology, but
can be disrupted in numerous diseases. The concept of targeting angiogenesis for treating …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
the developed world. The identification of the central role of vascular endothelial growth …

Purpose: Geographic atrophy (GA) is an advanced, vision-threatening form of age-related
macular degeneration (AMD) affecting approximately five million individuals worldwide. To …

There is a mutualistic symbiotic relationship between the components of the
photoreceptor/retinal pigment epithelium (RPE)/Bruch's membrane (BrMb)/choriocapillaris …

Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

Age-related macular degeneration (AMD) is a common and devastating disease that can
result in severe visual dysfunction. Over the last decade, great progress has been made in …

Age-related macular degeneration (AMD) is a devastating disease-causing vision loss in
millions of people around the world. In advanced stages of disease, death of photoreceptor …

Age-related macular degeneration (AMD) is a common disease that can result in severe
visual impairment. Abnormal regulation of the complement system has been implicated in its …

Abstract Age-Related Macular Degeneration (AMD) is a complex multifactorial disease
characterized in its early stages by lipoprotein accumulations in Bruch's Membrane (BrM) …

Outer retinal and renal glomerular functions rely on specialized vasculature maintained by
VEGF that is produced by neighboring epithelial cells, the retinal pigment epithelium (RPE) …