[HTML][HTML] A deep learning model to predict RNA-Seq expression of tumours from whole slide images

B Schmauch, A Romagnoni, E Pronier… - Nature …, 2020 - nature.com
Deep learning methods for digital pathology analysis are an effective way to address
multiple clinical questions, from diagnosis to prediction of treatment outcomes. These …

Single‐particle characterization by elastic light scattering

AV Romanov, MA Yurkin - Laser & Photonics Reviews, 2021 - Wiley Online Library
The field of light‐scattering characterization of single particles has seen a rapid growth over
the last 30 years largely due to the progress in measurement and simulation capabilities. In …

[HTML][HTML] The interface between biochemical signaling and cell mechanics shapes T lymphocyte migration and activation

M Millán-Salanova, M Vicente-Manzanares - European Journal of Cell …, 2022 - Elsevier
Abstract tT cells migrate to lymphoid organs to become activated through specific contacts
with antigen-presenting cells bearing foreign antigens. During migration and activation, T …

Label‐free identification of white blood cells using machine learning

M Nassar, M Doan, A Filby, O Wolkenhauer… - Cytometry Part …, 2019 - Wiley Online Library
White blood cell (WBC) differential counting is an established clinical routine to assess
patient immune system status. Fluorescent markers and a flow cytometer are required for the …

[HTML][HTML] Digital pathology analysis quantifies spatial heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 immune markers in triple-negative breast cancer

H Mi, C Gong, J Sulam, EJ Fertig, AS Szalay… - Frontiers in …, 2020 - frontiersin.org
Overwhelming evidence has shown the significant role of the tumor microenvironment (TME)
in governing the triple-negative breast cancer (TNBC) progression. Digital pathology can …

[HTML][HTML] A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution

M Bortolomeazzi, L Montorsi, D Temelkovski… - Nature …, 2022 - nature.com
Multiplexed imaging technologies enable the study of biological tissues at single-cell
resolution while preserving spatial information. Currently, high-dimension imaging data …

[HTML][HTML] Raman-based spectrophenotyping of the most important cells of the immune system

A Borek-Dorosz, AM Nowakowska… - Journal of Advanced …, 2022 - Elsevier
Introduction Human peripheral blood mononuclear cells (PBMCs) are a heterogeneous
population of cells that includes T and B lymphocytes. The total number of lymphocytes and …

Erythrocyte lysis and angle‐resolved light scattering measured by scanning flow cytometry result to 48 indices quantifying a gas exchange function of the human …

ES Yastrebova, VM Nekrasov, KV Gilev… - Cytometry Part …, 2023 - Wiley Online Library
Molecular/cell level of gas exchange function assumes the accurate measurement of
erythrocyte characteristics and rate constants concerning to molecules involved into the …

Precise label-free leukocyte subpopulation separation using hybrid acoustic-optical chip

XJ Hu, HL Liu, YX Jin, L Liang, DM Zhu, XQ Zhu… - Lab on a Chip, 2018 - pubs.rsc.org
Leukocyte subpopulations contain crucial physiological information; hence, precise and
specific leukocyte separation is very important for leukemia diagnosis and analysis …

[HTML][HTML] Towards Raman-Based Screening of Acute Lymphoblastic Leukemia-Type B (B-ALL) Subtypes

P Leszczenko, A Borek-Dorosz, AM Nowakowska… - Cancers, 2021 - mdpi.com
Simple Summary Acute lymphoblastic leukemia (ALL) is the most common pediatric
malignancy originating from abnormal lymphoid progenitor cells. Since ALL is genetically …