The regulation of gene expression is fundamental for life. Whereas the role of transcriptional
regulation of gene expression has been studied for several decades, it has been clear over …

Dysregulation of mRNA translation is a frequent feature of neoplasia. Many oncogenes and
tumour suppressors affect the translation machinery, making aberrant translation a …

Oxaliplatin resistance is a challenge in the treatment of colorectal cancer (CRC) patients.
Regulatory T cells (Tregs) are well known for their immunosuppressive roles, and targeting …

The nuclear factor‐κB (NF‐κB) transcription factor family has been considered the central
mediator of the inflammatory process and a key participant in innate and adaptive immune …

Tumor-suppressor Pdcd4 inhibits transformation and invasion and is downregulated in
cancers. So far, it has not been studied as to whether miRNAs, suppressing target …

Lung cancer is the leading cause of cancer-related deaths in the world, and non-small-cell
lung cancer (NSCLC) accounts for 80% of cases. MicroRNA-21 (miR-21) expression is …

• miR‐21 expression in cancer and other diseases• Mechanisms of miR‐21 elevation in
cancer: multi‐level regulatory control• Transcriptional control• Post‐trancriptional regulation• …

MicroRNAs are emerging as important regulators of cancer-related processes. The miR-21
microRNA is overexpressed in a wide variety of cancers and has been causally linked to …

The maintenance and preservation of distinct phases during the cell cycle is a highly
complex and coordinated process. It is regulated by phosphorylation—through the activity of …

MicroRNAs (miRNAs) are small noncoding RNA molecules that negatively control
expression of target genes in animals and plants. The microRNA-21 gene (mir-21) has been …