Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials

D Rawat, A Roy, S Maitra, A Gulati, P Khanna… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …

The role of antioxidants in the interplay between oxidative stress and senescence

A Varesi, S Chirumbolo, LIM Campagnoli, E Pierella… - Antioxidants, 2022 - mdpi.com
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus… - Intensive care …, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

The effects of vitamin C on respiratory, allergic and immunological diseases: an experimental and clinical-based review

MHE Ghalibaf, F Kianian, S Beigoli, S Behrouz… - …, 2023 - Springer
Vitamin C is used in modern medicine supplements for treatment of various disorders
associated with oxidative stress, inflammation and immune dysregulation. In this review …

Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis

J Li - Critical Care, 2018 - Springer
Two recent publications by Sheikh and Horner and Teng et al. reviewed studies on
incorporating vitamin C to treat septic patients; however, a meta-analysis was not offered in …

[HTML][HTML] Vitamin C therapy for routine care in septic shock (ViCTOR) trial: effect of intravenous vitamin C, thiamine, and hydrocortisone administration on inpatient …

ZU Mohamed, P Prasannan, M Moni… - Indian journal of …, 2020 - ncbi.nlm.nih.gov
Background Sepsis remains a leading cause of death worldwide despite advances in
management strategies. Preclinical and observational studies have found mortality benefit …

Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats

N Zhang, W Zhao, ZJ Hu, SM Ge, Y Huo, LX Liu… - Scientific Reports, 2021 - nature.com
Sepsis survivors present long-term cognitive deficits. The present study was to investigate
the effect of early administration of high-dose vitamin C on cognitive function in septic rats …

The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome

MG Traber, GR Buettner, RS Bruno - Redox biology, 2019 - Elsevier
Metabolic syndrome (MetS) is a constellation of cardiometabolic risk factors, which together
predict increased risk of more serious chronic diseases. We propose that one consequence …

Vitamin therapy in sepsis

EL Wald, CM Badke, LK Hintz, M Spewak… - Pediatric …, 2022 - nature.com
Vitamins are essential micronutrients with key roles in many biological pathways relevant to
sepsis. Some of these relevant biological mechanisms include antioxidant and anti …

Early use of high-dose vitamin C is beneficial in treatment of sepsis

SJ Lv, GH Zhang, JM Xia, H Yu, F Zhao - Irish Journal of Medical Science …, 2021 - Springer
Purpose Vitamin C has shown benefits in patients with sepsis in addition to standard therapy
recently. However, further evidence is required to verify the efficacy of vitamin C in clinical …