2H/4H-Chromenes—A versatile biologically attractive Scaffold
V Raj, J Lee - Frontiers in Chemistry, 2020 - frontiersin.org
2H/4H-chromene (2H/4H-ch) is an important class of heterocyclic compounds with versatile
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …
Design, synthesis, antimicrobial activity and computational studies of novel azo linked substituted benzimidazole, benzoxazole and benzothiazole derivatives
VR Mishra, CW Ghanavatkar, SN Mali… - … biology and chemistry, 2019 - Elsevier
Novel azo linked substituted benzimidazole, benzoxazole, and benzothiazole were
synthesized by diazo coupling and characterized by 1 H NMR, elemental analysis, FTIR and …
synthesized by diazo coupling and characterized by 1 H NMR, elemental analysis, FTIR and …
An insight into the synthesis and SAR of 2, 4-thiazolidinediones (2, 4-TZD) as multifunctional scaffold: a review
NS Sethi, DN Prasad, RK Singh - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …
Determination of potential inhibitors based on isatin derivatives against SARS-CoV-2 main protease (mpro): a molecular docking, molecular dynamics and structure …
VN Badavath, A Kumar, PK Samanta… - Journal of …, 2022 - Taylor & Francis
Abstract SARS-COV-2, the novel coronavirus and root of global pandemic COVID-19
caused a severe health threat throughout the world. Lack of specific treatments raised an …
caused a severe health threat throughout the world. Lack of specific treatments raised an …
Synthesis, characterization, anti-proliferative properties and DNA binding of benzochromene derivatives: Increased Bax/Bcl-2 ratio and caspase-dependent apoptosis …
MH Ahagh, G Dehghan, M Mehdipour… - Bioorganic …, 2019 - Elsevier
Amino-1-aryl-1H-benzo [f] chromene-2-carbonitrile derivatives were synthesized from three-
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4 …
Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P …
LM Al-Harbi, EA Al-Harbi, RM Okasha… - Journal of enzyme …, 2023 - Taylor & Francis
A series of 1 H-benzo [f] chromene moieties (4a–z) were synthesised under Ultrasonic
irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray …
irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray …
Ultrasonic‐assisted preparation of Co3O4 and Eu‐doped Co3O4 nanocatalysts and their application for solvent‐free synthesis of 2‐amino‐4H‐benzochromenes …
L Kafi‐Ahmadi, A Poursattar Marjani… - Applied …, 2021 - Wiley Online Library
Co3O4 and Eu‐doped Co3O4 nanocatalysts were synthesized through an ultrasonic‐
assisted solvothermal method and were characterized with X‐ray diffraction (XRD), Fourier …
assisted solvothermal method and were characterized with X‐ray diffraction (XRD), Fourier …
Synthesis, Cytotoxic Activity, Crystal Structure, DFT Studies and Molecular Docking of 3-Amino-1-(2,5-dichlorophenyl)-8-methoxy-1H-benzo[f]chromene-2 …
M El Gaafary, T Syrovets, H M. Mohamed… - Crystals, 2021 - mdpi.com
The target compound 3-amino-1-(2, 5-d ichlorophenyl)-8-methoxy-1 H-benzo [f]-chromene-2-
carbonitrile (4) was synthesized via a reaction of 6-methoxynaphthalen-2-ol (1), 2, 5 …
carbonitrile (4) was synthesized via a reaction of 6-methoxynaphthalen-2-ol (1), 2, 5 …
Synthesis and Evaluation of Some New 4H-Pyran Derivatives as Antioxidant, Antibacterial and Anti-HCT-116 Cells of CRC, with Molecular Docking, Antiproliferative …
Colorectal cancer oncogenesis is linked to dysbiosis, oxidative stress and overexpression of
CDK2. The 4 H-pyran scaffold is considered an antitumoral, antibacterial and antioxidant …
CDK2. The 4 H-pyran scaffold is considered an antitumoral, antibacterial and antioxidant …
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo [h] chromene
FF Alblewi, RM Okasha, ZM Hritani, HM Mohamed… - Bioorganic …, 2019 - Elsevier
Novel β-enaminonitrile/ester compounds (4, 6) and an imidate of 4 (9) were utilized as key
scaffolds for the synthesis of newly 2-substituted 4H-benzo [h] chromene (7, 8, 10, 11, 13 …
scaffolds for the synthesis of newly 2-substituted 4H-benzo [h] chromene (7, 8, 10, 11, 13 …