Normal development and function of the central nervous system involves a balance between
excitatory and inhibitory neurotransmission. Activity of both excitatory and inhibitory neurons …

Abstract α 2 δ proteins are membrane-anchored extracellular glycoproteins which are
abundantly expressed in the brain and the peripheral nervous system. They serve as …

The primary cilium is an organelle present in most adult mammalian cells that is considered
as an antenna for sensing the local microenvironment. Here, we use intact mouse …

L'inhibition est une des plus importantes découvertes de l'évolution. Elle est présente, avec
sa compagne la désinhibition, à tous les niveaux du vivant–moléculaire, cellulaire, social …

CDGSH iron–sulfur domain‐containing protein 2 (Cisd2), a protein that declines in an age‐
dependent manner, mediates lifespan in mammals. Cisd2 deficiency causes accelerated …

During development, GABA and glycine play major trophic and synaptic roles in the
establishment of the neuromotor system. In this review, we summarise the formation …

Abstract Background Ceiba pentandra (L.) Gaertn.(Malvaceae) is a plant documented
folklorically to be used in the management of epilepsy but with no scientific evidence to …

Developing neural circuits, including GABAergic circuits, switch receptor types. But the role
of early GABA receptor expression for establishment of functional inhibitory circuits remains …

Excitotoxic levels of released glutamate trigger a cascade of deleterious cellular events
leading to delayed neuronal death. This phenomenon implies extensive dysregulation in the …

The inferior olive (IO) is composed of electrically-coupled neurons that make climbing fiber
synapses onto Purkinje cells. Neurons in different IO subnuclei are inhibited by synapses …