[HTML][HTML] Correlates of protection against human rotavirus disease and the factors influencing protection in low-income settings
E Clarke, U Desselberger - Mucosal immunology, 2015 - Elsevier
Rotaviruses (RV) are the leading cause of gastroenteritis in infants and children worldwide
and are associated with high mortality predominately in low-income settings. The virus is …
and are associated with high mortality predominately in low-income settings. The virus is …
Viruses causing childhood diarrhoea in the developing world
The review highlights the importance of viral agents of gastroenteritis in developing
countries. Wider use of molecular techniques is resulting in rapid identification of new or …
countries. Wider use of molecular techniques is resulting in rapid identification of new or …
Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection
Neonatal rotavirus infections are predominantly asymptomatic. While an association with
gastrointestinal symptoms has been described in some settings, factors influencing …
gastrointestinal symptoms has been described in some settings, factors influencing …
Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses
Human milk contains a rich set of soluble, reducing glycans whose functions and
bioactivities are not well understood. Because human milk glycans (HMGs) have been …
bioactivities are not well understood. Because human milk glycans (HMGs) have been …
[HTML][HTML] Diversity in rotavirus–host glycan interactions: a “sweet” spectrum
Interaction with cellular glycans is a critical initial step in the pathogenesis of many infectious
agents. Technological advances in glycobiology have expanded the repertoire of studies …
agents. Technological advances in glycobiology have expanded the repertoire of studies …
The VP8* domain of neonatal rotavirus strain G10P [11] binds to type II precursor glycans
Naturally occurring bovine-human reassortant rotaviruses with a P [11] VP4 genotype exhibit
a tropism for neonates. Interaction of the VP8* domain of the spike protein VP4 with sialic …
a tropism for neonates. Interaction of the VP8* domain of the spike protein VP4 with sialic …
Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy: rotavirus host receptor and vaccine strategy
The success of the two rotavirus (RV) vaccines (Rotarix and RotaTeq) in many countries
endorses a live attenuated vaccine approach against RVs. However, the lower efficacies of …
endorses a live attenuated vaccine approach against RVs. However, the lower efficacies of …
Viral infections and neonatal necrotizing enterocolitis: a meta-analysis
CONTEXT Necrotizing enterocolitis (NEC) is a devastating intestinal disease affecting
preterm infants. Studies implicate viral infections in etiopathogenesis. OBJECTIVE To …
preterm infants. Studies implicate viral infections in etiopathogenesis. OBJECTIVE To …
Overview of the development, impacts, and challenges of live-attenuated oral rotavirus vaccines
OS Folorunso, OM Sebolai - Vaccines, 2020 - mdpi.com
Safety, efficacy, and cost-effectiveness are paramount to vaccine development. Following
the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe …
the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe …
Promoting appropriate management of diarrhea: a systematic review of literature for advocacy and action: UNICEF-PHFI series on newborn and child health, India
Background Scaling up of evidence-based management and prevention of childhood
diarrhea is a public health priority in India, and necessitates robust literature review, for …
diarrhea is a public health priority in India, and necessitates robust literature review, for …