Exosomes and other extracellular vesicles in host–pathogen interactions

JS Schorey, Y Cheng, PP Singh, VL Smith - EMBO reports, 2015 - embopress.org
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

[HTML][HTML] Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles

N Regev-Rudzki, DW Wilson, TG Carvalho, X Sisquella… - Cell, 2013 - cell.com
Cell-cell communication is an important mechanism for information exchange promoting cell
survival for the control of features such as population density and differentiation. We …

Exosomes and other extracellular vesicles: the new communicators in parasite infections

G Coakley, RM Maizels, AH Buck - Trends in parasitology, 2015 - cell.com
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

Exosome as a novel shuttle for delivery of therapeutics across biological barriers

CK Das, BC Jena, I Banerjee, S Das… - Molecular …, 2018 - ACS Publications
The effective delivery of target-specific siRNA to the brain by exploiting the exosomes
derived from dendritic cells renders the paradigm shift for the prospective use of nanosized …

malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Innate sensing of malaria parasites

RT Gazzinelli, P Kalantari, KA Fitzgerald… - Nature Reviews …, 2014 - nature.com
Innate immune receptors have a key role in immune surveillance by sensing
microorganisms and initiating protective immune responses. However, the innate immune …

Cytokines and chemokines in cerebral malaria pathogenesis

J Dunst, F Kamena, K Matuschewski - Frontiers in cellular and …, 2017 - frontiersin.org
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system

PY Mantel, AN Hoang, I Goldowitz, D Potashnikova… - Cell host & …, 2013 - cell.com
Humans and mice infected with different Plasmodium strains are known to produce
microvesicles derived from the infected red blood cells (RBCs), denoted RMVs. Studies in …

Platelet microvesicles in health and disease

I Melki, N Tessandier, A Zufferey, E Boilard - platelets, 2017 - Taylor & Francis
Interest in cell-derived extracellular vesicles and their physiological and pathological
implications is constantly growing. Microvesicles, also known as microparticles, are small …