The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …

Prefrontal cortex (PFC) is postulated to exert" top-down control" on information processing
throughout the brain to promote specific behaviors. However, pathways mediating top-down …

Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …

Long-range synchronization of neural oscillations correlates with distinct behaviors, yet its
causal role remains unproven. In mice, tests of avoidance behavior evoke increases in theta …

Anxiety is an aversive mood reflecting the anticipation of potential threats. The ventral
hippocampus (vH) is a key brain region involved in the genesis of anxiety responses …

The concept of a dynamic excitation/inhibition balance tuned by circuit disinhibition, which
can shape information flow during complex behavioral tasks, has arisen as an important and …

In response to stressors, individuals adopt different behavioral styles, which are essential for
survival and form the basis of differential susceptibility to stress-related disorders …

Attentional modulation of sensory processing is a key feature of cognition; however, its
neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of …

Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of
which have been only partially elucidated. The hippocampus serves as a major target of …