Almost all commercial proteins are purified using ammonium sulfate precipitation. Protein-
polymer conjugates are synthesized from pure starting materials, and the struggle to …

Liquid–liquid phase separation (LLPS) underlies the formation of membrane-free organelles
in eukaryotic cells and plays an important role in the development of some diseases. The …

When developping selective crystallization or precipitation processes, biopharmaceutical
modalities require empirical screenings and analytics tailored to the specific needs of the …

Interactions between a model protein (bovine serum albumin—BSA) and the cationic
polyelectrolyte, chitosan (Chi), have been characterized by turbidimetry, circular dichroism …

The present study aimed to produce a macroporous monolithic cation-exchanger and
evaluate the effect of temperature on the thermodynamic behavior of lysozyme adsorption …

Thermodynamic relations between the solubility of a protein and the solution pH are
presented in this work. The hypotheses behind the development are that the protein …

Phase diagrams and solubility curves for engineering of crystallization for interferon gamma
have been developed by small scale precipitation and crystallization experiments. A scale …

When placed in the same environment, biochemically unrelated macromolecules influence
each other's biological function through macromolecular crowding (MC) effects. This has …

Dielectric continuum or implicit solvent models provide a significant reduction in
computational cost when accounting for the salt-mediated electrostatic interactions of …

Protein phase diagrams are a tool to investigate the cause and consequence of solution
conditions on protein phase behavior. The effects are scored according to aggregation …