Cardiac natriuretic peptides

JP Goetze, BG Bruneau, HR Ramos, T Ogawa… - Nature Reviews …, 2020 - nature.com
Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …

Endothelial dysfunction in pulmonary hypertension: cause or consequence?

K Kurakula, VFED Smolders, O Tura-Ceide… - Biomedicines, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare, complex, and progressive disease that is
characterized by the abnormal remodeling of the pulmonary arteries that leads to right …

Alveolar cells under mechanical stressed niche: critical contributors to pulmonary fibrosis

J Yang, X Pan, L Wang, G Yu - Molecular Medicine, 2020 - Springer
Pulmonary fibrosis arises from the repeated epithelial mild injuries and insufficient repair
lead to over activation of fibroblasts and excessive deposition of extracellular matrix, which …

Mechanotransduction regulates the interplays between alveolar epithelial and vascular endothelial cells in lung

C Lin, X Zheng, S Lin, Y Zhang, J Wu, Y Li - Frontiers in Physiology, 2022 - frontiersin.org
Mechanical stress plays a critical role among development, functional maturation, and
pathogenesis of pulmonary tissues, especially for the alveolar epithelial cells and vascular …

Sex differences in pulmonary hypertension

H Morris, N Denver, R Gaw, H Labazi… - Clinics in Chest …, 2021 - chestmed.theclinics.com
Pulmonary hypertension (PH) is defined as a mean pulmonary arterial pressure of greater
than 20 mm Hg at rest. It is characterized by a progressive increase in pulmonary arterial …

Pulmonary hypertension in interstitial lung disease: screening, diagnosis and treatment

J Behr, SD Nathan - Current Opinion in Pulmonary Medicine, 2021 - journals.lww.com
Pulmonary hypertension in interstitial lung disease: screeni... : Current Opinion in
Pulmonary Medicine Pulmonary hypertension in interstitial lung disease: screening …

Right heart catheterization—Background, physiological basics, and clinical implications

GM Kubiak, A Ciarka, M Biniecka… - Journal of clinical …, 2019 - mdpi.com
The idea of right heart catheterization (RHC) grew in the milieu of modern thinking about the
cardiovascular system, influenced by the experiments of William Harvey, which were …

Galectin-3: a harbinger of reactive oxygen species, fibrosis, and inflammation in pulmonary arterial hypertension

DJR Fulton, X Li, Z Bordan, Y Wang… - Antioxidants & Redox …, 2019 - liebertpub.com
Significance: Pulmonary arterial hypertension (PAH) is a progressive disease arising from
the narrowing of pulmonary arteries (PAs) resulting in high pulmonary arterial blood …

Dysregulated immunity in pulmonary hypertension: From companion to composer

TC Funk-Hilsdorf, F Behrens, J Grune… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) represents a grave condition associated with high morbidity
and mortality, emphasizing a desperate need for innovative and targeted therapeutic …

The role of macrophages in pulmonary hypertension: Pathogenesis and targeting

S Chen, D Yan, A Qiu - International Immunopharmacology, 2020 - Elsevier
Pulmonary hypertension (PH) is a pathophysiological disorder that can complicate most
cardiovascular and respiratory diseases and may involve multiple clinical conditions, but its …