Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

Abstract Poloxamer 407 copolymer (ethylene oxide and propylene oxide blocks) shows
thermoreversible properties, which is of the utmost interest in optimising drug formulation …

Pluronic® block copolymers are found to be an efficient drug delivery system with multiple
effects. The incorporation of drugs into the core of the micelles formed by Pluronic® results …

Stem cell transplantation via direct injection is a minimally invasive strategy being explored
for treatment of a variety of injuries and diseases. Injectable hydrogels with shear moduli< …

Poor drug solubility remains a significant and frequently encountered problem for
pharmaceutical scientists. The ability of lipid-based formulations to facilitate gastrointestinal …

Limited solubility and hepatic first-pass metabolism are the main causes of low
bioavailability of anti-schizophrenic drug, Clozapine (CZP). The objective of the study was to …

Pluronicв block copolymers are recognized pharmaceutical excipients listed in the US and
British Pharmacopoeia. The incorporation of drugs into Pluronic micelles results in …

Polymeric nanofibers have potential as tissue engineering scaffolds, as they mimic the
nanoscale properties and structural characteristics of native extracellular matrix (ECM) …

Drug efflux transporters can influence the absorption, tissue distribution and elimination of
many therapeutic agents. Modulation of drug efflux transporter activity is being explored as a …

Erosion behaviour governs the use of physical hydrogels in biomedical applications ranging
from controlled release to cell encapsulation. Genetically engineered protein hydrogels offer …