Alterations in central fatigue by pharmacological manipulations of neurotransmitters in normal and high ambient temperature

B Roelands, R Meeusen - Sports Medicine, 2010 - Springer
The scientific evidence is reviewed for the involvement of the brain monoamines serotonin,
dopamine and noradrenaline (norepinephrine) in the onset of fatigue, in both normal and …

Neurobiology of 3, 4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

RA Glennon, R Young - Brain research bulletin, 2016 - Elsevier
Synthetic cathinones are analogs of cathinone or β-ketoamphetamine–the major
psychostimulant component of the shrub Catha edulis or khat. Cathinone analogs–though …

The novel recreational drug 3, 4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats

SM Aarde, PK Huang, KM Creehan, TJ Dickerson… - …, 2013 - Elsevier
Recreational use of the cathinone derivative 3, 4-methylenedioxypyrovalerone (MDPV;“bath
salts”) has increased worldwide in past years, accompanied by accounts of health and legal …

In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3, 4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in …

SM Aarde, KM Creehan, SA Vandewater… - …, 2015 - Springer
Rationale Numerous substituted cathinone drugs have appeared in recreational use. This
variety is often a response to legal actions; the scheduling of 3, 4 …

Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats

MJ Wright Jr, D Angrish, SM Aarde, DJ Barlow… - 2012 - journals.plos.org
The drug 4-methylmethcathinone (4-MMC; aka, mephedrone, MMCAT,“plant food”,“bath
salts”) is a recent addition to the list of popular recreational psychomotor-stimulant …

A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats

ML Miller, AY Moreno, SM Aarde, KM Creehan… - Biological …, 2013 - Elsevier
BACKGROUND: There are no approved pharmacotherapies for d-methamphetamine
(METH) addiction and existing therapies have limited efficacy. Advances in using …

Implant-forming polymeric 19F MRI-tracer with tunable dissolution

K Kolouchova, D Jirak, O Groborz, O Sedlacek… - Journal of Controlled …, 2020 - Elsevier
Magnetic resonance imaging (MRI) using 19 F-based tracers has emerged as a promising
multi-purpose noninvasive diagnostic tool and its application requires the use of various 19 …

Trace amine-associated receptor 1 regulation of methamphetamine-induced neurotoxicity

NB Miner, JS Elmore, MH Baumann, TJ Phillips… - Neurotoxicology, 2017 - Elsevier
Trace amine-associated receptor 1 (TAAR1) is activated by methamphetamine (MA) and
modulates dopaminergic (DA) function. Although DA dysregulation is the hallmark of MA …

Methiopropamine and its acute behavioral effects in mice: is there a gray zone in new psychoactive substances users?

F De-Giorgio, S Bilel, M Tirri, R Arfè, C Trapella… - International Journal of …, 2020 - Springer
Methiopropamine is a structural analog of methamphetamine that is categorized as a novel
psychoactive substance. It primarily acts as a norepinephrine–dopamine reuptake inhibitor …

Effects of acute and chronic systemic methamphetamine on respiratory, cardiovascular and metabolic function, and cardiorespiratory reflexes

SF Hassan, TA Wearne, JL Cornish… - The Journal of …, 2016 - Wiley Online Library
Key points Methamphetamine (METH) abuse is escalating worldwide, with the most
common cause of death resulting from cardiovascular failure and hyperthermia; however …