A quantification of gastric and duodenal fluid volumes in older adults using MRI

C Demeester, M Van der Veken, J Brouwers… - International Journal of …, 2024 - Elsevier
Older adults are an inherently heterogeneous population with various underlying
pathologies, medication use, and habits. In this study, the variability of this population was …

Vitamin C improves dasatinib concentrations under hypochlorhydric conditions of the simulated stomach duodenum model

FS Moghrabi, A Aburub, HM Fadda - Pharmaceutical Research, 2022 - Springer
Purpose pH-dependent drug-drug interactions (DDIs) with poorly soluble, weakly basic
drugs may lead to clinical implications. Dasatinib is a tyrosine kinase inhibitor with reduced …

Relative Bioavailability Assessment of Solid Forms by An Artificial Stomach and Duodenum Apparatus

Y Guo, A Byer-Alcorace, C Thomas, S Piekos… - Journal of …, 2024 - Elsevier
In this work, the ability of the artificial stomach and duodenum (ASD) model to predict
bioavailability in rats was investigated using a poorly soluble model compound, BI-639667 …