With the advent of the sustainable development goals, the field of global child health has
shifted its focus from reducing mortality to improving health, nutrition and development …

The lifespan is influenced by adverse childhood experiences that create predispositions to
poor health outcomes. Here we propose an allostatic framework of childhood experiences …

Recently, biological aging has been quantified in DNA-methylation samples of older adults
and applied as so-called “methylation profile scores”(MPSs) in separate target samples …

Background Early-life exposure increases health risks throughout an individual's lifetime.
Biological aging is influenced by early-life risks as a key process of disease development …

Although stress and adversity are largely universal experiences, people exposed to greater
hardship are at increased risk for negative health consequences. Recent studies identify …

Abstract Frailty and Biological Age are two closely related concepts; however, frailty is a
multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a …

Life history theory applied to human development stipulates that humans have evolved to
detect and encode information from the early developmental environment that entrain …

Method. We use longitudinal data from children and adolescents ages 8-18 (N= 428, M
age= 12.15 years) from the Texas Twin Project. Participants contributed two waves of …

This article examines the relationship between social inequity and the immune system,
emphasizing some of the many ways that systemic racism and other forms of marginalization …

Increasing research shows pubertal development accelerates following threats while it
decelerates following deprivation. Yet, these environmental stressors are unlikely to occur in …