Amyotrophic lateral sclerosis is characterised by the progressive loss of motor neurons in
the brain and spinal cord. This neurodegenerative syndrome shares pathobiological …

Considerable progress has been made in unraveling the genetic etiology of amyotrophic
lateral sclerosis (ALS), the most common form of adult-onset motor neuron disease and the …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of the motor pathways,
invariably leading to death within a few years of onset. Most cases of ALS are sporadic, but …

Mutations in the cytosine‐5 RNA methyltransferase NSun2 cause microcephaly and other
neurological abnormalities in mice and human. How post‐transcriptional methylation …

The number of studies on non-coding RNAs has increased substantially in recent years
owing to their importance in gene regulation. However, the biological functions of small …

Transfer RNA (tRNA) is traditionally considered to be an adaptor molecule that helps
ribosomes to decode messenger RNA (mRNA) and synthesize protein. Recent studies have …

Amyotrophic lateral sclerosis (ALS) is a devastating, uniformly lethal degenerative disorder
of motor neurons that overlaps clinically with frontotemporal dementia (FTD). Investigations …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of motor neurons
leading to death from respiratory failure within about 3 years of symptom onset. A family …

Sporadic amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
diseases; most patients die within 3 to 4 years after symptom onset. Oxidative stress is a …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with a substantial
heritable component. In pedigrees affected by its familial form, incomplete penetrance is …