Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Antibody tests for identification of current and past infection with SARS‐CoV‐2

T Fox, J Geppert, J Dinnes, K Scandrett… - Cochrane database …, 2022 - cochranelibrary.com
Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

D Shin, R Mukherjee, D Grewe, D Bojkova, K Baek… - Nature, 2020 - nature.com
The papain-like protease PLpro is an essential coronavirus enzyme that is required for
processing viral polyproteins to generate a functional replicase complex and enable viral …

Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA. 1 and BA. 2 by convalescent and vaccine serum and monoclonal antibodies

A Wilhelm, M Widera, K Grikscheit, T Toptan… - …, 2022 - thelancet.com
Summary Background In recent months, Omicron variants of SARS-CoV-2 have become
dominant in many regions of the world, and case numbers with Omicron subvariants BA. 1 …

[HTML][HTML] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe… - Immunity, 2021 - cell.com
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …

Detection of SARS-CoV-2 in raw and treated wastewater in Germany–suitability for COVID-19 surveillance and potential transmission risks

S Westhaus, FA Weber, S Schiwy, V Linnemann… - Science of The Total …, 2021 - Elsevier
Wastewater-based monitoring of the spread of the new SARS-CoV-2 virus, also referred to
as wastewater-based epidemiology (WBE), has been suggested as a tool to support …

SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients

J Korth, B Wilde, S Dolff, OE Anastasiou… - Journal of Clinical …, 2020 - Elsevier
Background The novel coronavirus SARS-CoV-2 is associated with a severe respiratory
manifestation, COVID-19, and presents a challenge for healthcare systems worldwide …

COVID-19 antibody tests and their limitations

G Liu, JF Rusling - ACS sensors, 2021 - ACS Publications
COVID-19, caused by the SARS-CoV-2 virus, has developed into a global health crisis,
causing over 2 million deaths and changing people's daily life the world over. Current main …

Glycyrrhizin effectively inhibits SARS-CoV-2 replication by inhibiting the viral main protease

L van de Sand, M Bormann, M Alt, L Schipper… - Viruses, 2021 - mdpi.com
The outbreak of SARS-CoV-2 developed into a global pandemic affecting millions of people
worldwide. Despite one year of intensive research, the current treatment options for SARS …

The comparative clinical performance of four SARS-CoV-2 rapid antigen tests and their correlation to infectivity in vitro

N Kohmer, T Toptan, C Pallas, O Karaca… - Journal of clinical …, 2021 - mdpi.com
Due to globally rising numbers of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infections, resources for real-time reverse-transcription polymerase chain reaction …