Arylamine N‐acetyltransferases (NAT s) are polymorphic drug‐metabolizing enzymes,
acetylating arylamine carcinogens and drugs including hydralazine and sulphonamides …

Tuberculosis (TB), although a curable disease, is still one of the most difficult infections to
treat. Mycobacterium tuberculosis infects 10 million people worldwide and kills 1.5 million …

Protein crystals obtained in initial screens typically require optimization before they are of X-
ray diffraction quality. Seeding is one such optimization method. In classical seeding …

Fusarium endophytes damage cereal crops and contaminate produce with mycotoxins.
Those fungi overcome the main chemical defence of host via detoxification by a malonyl …

This study explored the antitubercular properties of fucoxanthin, a marine carotenoid,
against clinical isolates of Mycobacterium tuberculosis (Mtb). Two vital enzymes involved in …

Arylamines constitute a large group of industrial chemicals detoxified by certain bacteria
through conjugation reactions catalyzed by N-acetyltransferase (NAT) enzymes. NAT …

Crystallization of membrane proteins is a critical step for uncovering atomic resolution 3-D
structures and elucidating structure–function relationships. Microseeding, the process of …

We report the biological evaluation of 5‐(5‐nitrothiophen‐2‐yl)‐4, 5‐dihydro‐1H‐pyrazole
derivatives against bacteria, eukaryotic cell lines and the assessment of their mechanisms of …

Background The mouse has three arylamine N-acetyltransferase genes,(MOUSE)
Nat1,(MOUSE) Nat2 and (MOUSE) Nat3. These are believed to correspond to (HUMAN) …

Drug-recalcitrant infections are a leading global-health concern. Bacterial cells benefit from
phenotypic variation, which can suggest effective antimicrobial strategies. However, probing …