K Vázquez-Arreguín, D Tantin - Biochimica Et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
The metazoan-specific POU domain transcription factor family comprises activities underpinning developmental processes such as embryonic pluripotency and neuronal …
Head and neck cancer accounts for an estimated 47,560 new cases and 11,480 deaths annually in the United States, the majority of which are squamous cell carcinomas (HNSCC) …
Abstract The Octamer-binding proteins (Oct) are a group of highly conserved transcription factors that specifically bind to the octamer motif (ATGCAAAT) and closely related …
VEH Wang, T Schmidt, J Chen, PA Sharp… - Molecular and Cellular …, 2004 - Taylor & Francis
Oct-1 is a sequence-specific DNA binding transcription factor that is believed to regulate a large group of tissue-specific and ubiquitous genes. Both Oct-1 and the related but tissue …
EV Pankratova, AG Stepchenko… - Nucleic Acids …, 2016 - academic.oup.com
Oct-1 transcription factor has various functions in gene regulation. Its expression level is increased in several types of cancer and is associated with poor survival prognosis. Here we …
NN Luchina, IV Krivega, EV Pankratova - Immunology letters, 2003 - Elsevier
POU homeodomain proteins are important regulators of ubiquitous as well as tissue-specific transcription. Ubiquitously expressed Oct-1 and tissue-specific Oct-2 proteins are members …
EV Pankratova, AG Stepchenko, ID Krylova… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Abstract Oct-1 (POU2F1) is a DNA-binding transcription regulator and its level being highly increased in many human cancers. Oct-1 is present in the human cells as a family of …
AG Stepchenko, TN Portseva, IA Glukhov… - Scientific Reports, 2021 - nature.com
The emergence of new primate-specific genes is an essential factor in human and primate brain development and functioning. POU2F1/Oct-1 is a transcription regulator in higher …
FQ Zhao, Y Zheng, B Dong, T Oka - Gene, 2004 - Elsevier
The ubiquitously expressed transcription factor Oct-1, a member of the POU domain factors, is involved in the regulation of expression of many tissue-specific and house-keeping genes …