Aflatoxin B1 toxicity and protective effects of curcumin: Molecular mechanisms and clinical implications

C Dai, E Tian, Z Hao, S Tang, Z Wang, G Sharma… - Antioxidants, 2022 - mdpi.com
One of the most significant classes of mycotoxins, aflatoxins (AFTs), can cause a variety of
detrimental outcomes, including cancer, hepatitis, aberrant mutations, and reproductive …

Research progress in toxicological effects and mechanism of aflatoxin B1 toxin

C Li, X Liu, J Wu, X Ji, Q Xu - PeerJ, 2022 - peerj.com
Fungal contamination of animal feed can severely affect the health of farm animals, and
result in considerable economic losses. Certain filamentous fungi or molds produce toxic …

Anti-inflammation-based treatment of atherosclerosis using Gliclazide-loaded biomimetic nanoghosts

Z Karami, J Mehrzad, M Akrami, S Hosseinkhani - Scientific reports, 2023 - nature.com
In the study, a biomimetic platform for anti-inflammatory-based treatment of atherosclerotic
plaque was developed. Gliclazide (GL) as an anti-inflammasome agent was encapsulated in …

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

C Dai, G Sharma, G Liu, J Shen, B Shao, Z Hao - Environmental Pollution, 2024 - Elsevier
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …

Lactobacillus plantarum C88 protects against aflatoxin B1-induced liver injury in mice via inhibition of NF-κB–mediated inflammatory responses and excessive …

L Huang, Z Zhao, C Duan, C Wang, Y Zhao, G Yang… - BMC microbiology, 2019 - Springer
Background Probiotics play an important role in the human and animal defense against liver
damage. However, the protective mechanism of Lactobacillus plantarum C88 on chronic …

[HTML][HTML] Yeast polysaccharide mitigated oxidative injury in broilers induced by mixed mycotoxins via regulating intestinal mucosal oxidative stress and hepatic …

J Zhang, Y Fang, Y Fu, S Jalukar, J Ma, Y Liu, Y Guo… - Poultry Science, 2023 - Elsevier
This study was aimed to investigate the effects of yeast polysaccharides (YPS) on growth
performance, intestinal health, and aflatoxin metabolism in livers of broilers fed diets …

Metabolic disruption by naturally occurring mycotoxins in circulation: a focus on vascular and bone homeostasis dysfunction

AM Malvandi, S Shahba, J Mehrzad… - Frontiers in nutrition, 2022 - frontiersin.org
Naturally occurring food/feed contaminants have become a significant global issue due to
animal and human health implications. Despite risk assessments and legislation setpoints …

Lycopene as a Therapeutic Agent against Aflatoxin B1-Related Toxicity: Mechanistic Insights and Future Directions

M Li, S Tang, X Peng, G Sharma, S Yin, Z Hao, J Li… - Antioxidants, 2024 - mdpi.com
Aflatoxin (AFT) contamination poses a significant global public health and safety concern,
prompting widespread apprehension. Of the various AFTs, aflatoxin B1 (AFB1) stands out for …

Aflatoxin B1 damaged structural barrier through Keap1a/Nrf2/MLCK signaling pathways and immune barrier through NF-κB/TOR signaling pathways in gill of grass …

XN He, ZZ Zeng, L Feng, P Wu, WD Jiang, Y Liu… - Aquatic Toxicology, 2023 - Elsevier
Aquafeeds are susceptible to contamination caused by aflatoxin B1 (AFB1). The gill of fish is
an important respiratory organ. However, few studies have investigated the effects of dietary …

Neuroimmune disruptions from naturally occurring levels of mycotoxins

S Shahba, J Mehrzad, AM Malvandi - Environmental science and pollution …, 2021 - Springer
Substantial pieces of evidence support the potential of exogenous toxins in disrupting
neuroimmune homeostasis. It appears that mycotoxins are one of the noticeable sources of …