Molecular mechanisms and physiological importance of circadian rhythms

A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Circadian Rhythms and Sleep in Drosophila melanogaster

C Dubowy, A Sehgal - Genetics, 2017 - academic.oup.com
The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Genome Sequence of the Pea Aphid Acyrthosiphon pisum

International Aphid Genomics Consortium - PLoS biology, 2010 - journals.plos.org
Aphids are important agricultural pests and also biological models for studies of insect-plant
interactions, symbiosis, virus vectoring, and the developmental causes of extreme …

[图书][B] Insect physiology and biochemistry

JL Nation Sr - 2022 - taylorfrancis.com
Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

Post-translational modifications regulate the ticking of the circadian clock

M Gallego, DM Virshup - Nature reviews Molecular cell biology, 2007 - nature.com
Getting a good night's sleep is on everyone's to-do list. So is, no doubt, staying awake during
late afternoon seminars. Our internal clocks control these and many more workings of the …

Immunity and other defenses in pea aphids, Acyrthosiphon pisum

NM Gerardo, B Altincicek, C Anselme, H Atamian… - Genome biology, 2010 - Springer
Background Recent genomic analyses of arthropod defense mechanisms suggest
conservation of key elements underlying responses to pathogens, parasites and stresses. At …

Clocks not winding down: unravelling circadian networks

EE Zhang, SA Kay - Nature reviews Molecular cell biology, 2010 - nature.com
An intrinsic clock enables an organism to anticipate environmental changes and use energy
sources more efficiently, thereby conferring an adaptive advantage. Having an intrinsic clock …

Molecular genetic analysis of circadian timekeeping in Drosophila

PE Hardin - Advances in genetics, 2011 - Elsevier
A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first
clock gene—the period (per) gene. The per gene is a central player within a transcriptional …

Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression

SM Siepka, SH Yoo, J Park, W Song, V Kumar, Y Hu… - Cell, 2007 - cell.com
Using a forward genetics ENU mutagenesis screen for recessive mutations that affect
circadian rhythmicity in the mouse, we isolated a long period (∼ 26 hr) circadian mutant …

The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease

K Davidson, AM Pickering - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
The proteasome is a large multi-subunit protease responsible for the degradation and
removal of oxidized, misfolded, and polyubiquitinated proteins. The proteasome plays …