Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a
novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides …

Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …

Genome sequencing has resulted in the identification of a large number of uncharacterized
genes with unknown functions. It is widely recognized that determination of the intracellular …

Claudins (Cldn) are essential membrane proteins of tight junctions (TJs), which form the
paracellular permselective barrier. They are produced by a multi-gene family of 24 reported …

Antimicrobial peptides (AMPs) derived from natural toxins and venoms offer a promising
alternative source of antibiotics. Here, through structure-function-guided design, we convert …

The growing prevalence of resistance to antibiotics motivates the search for new
antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane …

ATR responds to mechanical stress at the nuclear envelope and mediates envelope-
associated repair of aberrant topological DNA states. By combining microscopy, electron …

The fern Pteris vittata tolerates and hyperaccumulates exceptionally high levels of the toxic
metalloid arsenic, and this trait appears unique to the Pteridaceae. Once taken up by the …

In its natural habitats, Bacillus subtilis is exposed to changing osmolarity, necessitating
adaptive stress responses. Transcriptomic and proteomic approaches can provide a picture …

The separation of membrane protein complexes can be divided into two categories. One
category, which is operated on a relatively large scale, aims to purify the membrane protein …