Challenges and opportunities in cryo-EM single-particle analysis

D Lyumkis - Journal of Biological Chemistry, 2019 - ASBMB
Cryogenic electron microscopy (cryo-EM) enables structure determination of
macromolecular objects and their assemblies. Although the techniques have been …

Automated data collection in single particle electron microscopy

YZ Tan, A Cheng, CS Potter… - Journal of Electron …, 2015 - academic.oup.com
Automated data collection is an integral part of modern workflows in single particle electron
microscopy (EM) research. This review surveys the software packages available for …

AutoDetect-mNP: an unsupervised machine learning algorithm for automated analysis of transmission electron microscope images of metal nanoparticles

X Wang, J Li, HD Ha, JC Dahl, JC Ondry… - Jacs Au, 2021 - ACS Publications
The synthesis quality of artificial inorganic nanocrystals is most often assessed by
transmission electron microscopy (TEM) for which high-throughput advances have …

High-throughput identification of crystalline natural products from crude extracts enabled by microarray technology and microED

DA Delgadillo, JE Burch, LJ Kim… - ACS Central …, 2023 - ACS Publications
The structural determination of natural products (NPs) can be arduous because of sample
heterogeneity. This often demands iterative purification processes and characterization of …

Automated Gold Nanorod Spectral Morphology Analysis Pipeline

SP Gleason, JC Dahl, M Elzouka, X Wang, DO Byrne… - ACS …, 2024 - ACS Publications
The development of a colloidal synthesis procedure to produce nanomaterials with high
shape and size purity is often a time-consuming, iterative process. This is often due to …

An artificial intelligence's interpretation of complex high-resolution in situ transmission electron microscopy data

X Wang, C Yan, JC Ondry, V Bodiwala, P Ercius… - Matter, 2024 - cell.com
Complicated nano-and atomic-scale processes with sub-angstrom spatial resolution and
millisecond time resolution visualized by in situ transmission electron microscopy (TEM) are …

[PDF][PDF] 透射电子显微镜技术新进展及其在地球和行星科学研究中的应用

唐旭, 李金华 - 地球科学, 2021 - earth-science.net
近年来, 各种微束分析技术的快速发展及其在地球和行星科学领域的广泛应用,
极大地推动了纳米地球科学和行星科学的学科发展和科学研究. 透射电子显微镜(简称透射电镜) …

DNA Nanotags for Multiplexed Single-Particle Electron Microscopy and In Situ Electron Cryotomography

Y Chen, Y Huang, YR Yang - JACS Au, 2024 - ACS Publications
DNA nanostructures present new opportunities as Nanotags for electron microscopy (EM)
imaging, leveraging their high programmability, unique shapes, biomolecule conjugation …

Miniaturizing EM sample preparation: opportunities, challenges, and “visual proteomics”

SA Arnold, SA Müller, C Schmidli, A Syntychaki… - …, 2018 - Wiley Online Library
This review compares and discusses conventional versus miniaturized specimen
preparation methods for transmission electron microscopy (TEM). The progress brought by …

Co-encapsulation of Coumarin and Q10 into Solid Lipid Nanoparticles for Wound Healing

MA Alrubaye, Z Lafi, MNA Hajleh… - Journal of Drug Delivery …, 2025 - Elsevier
Wound healing often requires therapeutic interventions to enhance tissue repair and prevent
infections. Solid lipid nanoparticles (SLNs) have emerged as a promising drug delivery …