In this review, we summarize current knowledge regarding the epigenetics of age-related
diseases, focusing on those studies that have described DNA methylation landscape in …

Age estimation from DNA methylation markers has seen an exponential growth of interest,
not in the least from forensic scientists. The current published assays, however, can still be …

Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an
increased risk of myeloid malignancies. We performed an integrative characterization of …

A growing amount of evidences indicates that inflammaging–the chronic, low grade
inflammation state characteristic of the elderly–is the result of genetic as well as …

Background: Current epigenetic studies on aging are dominated by the cross-sectional
design that correlates subjects' ages or age groups with their measured epigenetic profiles …

The identification and validation of drugs that promote health during aging (“geroprotectors”)
are key to the retardation or prevention of chronic age‐related diseases. Here, we found that …

In recent years, new DNA methylation variants have been reported in genes biologically
relevant to Alzheimer's disease (AD) in human brain tissue. However, this AD-specific …

Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral
integration and latency. However, epigenetic changes in the HIV-1-infected host genome …

Epigenetic remodeling is one of the major features of the aging process. We recently
demonstrated that DNA methylation of ELOVL2 and FHL2 CpG islands is highly correlated …

Sex differences in the prevalence of psychiatric disorders are well documented, with
exposure to stress during gestation differentially impacting females and males. We explored …