The therapeutic efficacy of antiretroviral drugs as well as challenges and side effects against
the human immunodeficiency virus is well documented and reviewed. Evidence is available …

Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis characterized by
cell shrinkage and cell membrane scrambling. Eryptotic erythrocytes are rapidly cleared …

End stage renal disease (ESRD) invariably leads to anemia which has been mainly
attributed to compromised release of erythropoietin from the defective kidneys with …

Suicidal erythrocyte death or eryptosis contributes to or even accounts for anemia in a wide
variety of clinical conditions, such as iron deficiency, dehydration, hyperphosphatemia …

Background/Aims: The viral integrase enzyme inhibitor dolutegravir is utilized for the
treatment of immunodeficiency virus (HIV) infection. Knowledge on cytotoxicity of …

Background/Aims: The mammalian target of rapamycin (mTOR) inhibitor temsirolimus is
utilized for the treatment of malignancy. Temsirolimus is at least in part effective by triggering …

Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase
inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The …

Background: Eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and
phosphatidylserine-translocation, is triggered by fever and inflammation. Signaling includes …

Abstract Background/Aims: The steroidal aromatase inactivator exemestane blocks estrogen
biosynthesis and is thus employed for the prevention and treatment of breast cancer …