Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …
limited understanding of its clinical pathogenic spectrum of infection and disease …
Xpert® MTB/RIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance
Global TB control efforts have been severely hampered by the lack of diagnostic tests that
are accurate, simple to use and can be applied at the point of clinical care. This has been …
are accurate, simple to use and can be applied at the point of clinical care. This has been …
Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta-analysis of …
H Getahun, W Kittikraisak, CM Heilig, EL Corbett… - PLoS …, 2011 - journals.plos.org
Background The World Health Organization recommends the screening of all people living
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …
Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive …
SD Lawn, AD Kerkhoff, M Vogt… - The Lancet infectious …, 2012 - thelancet.com
Background The diagnostic accuracy of sputum smear microscopy and routine chest
radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow …
radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow …
Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study
Background The World Health Organization has endorsed the Xpert MTB/RIF assay for
investigation of patients suspected of having tuberculosis (TB). However, its utility for routine …
investigation of patients suspected of having tuberculosis (TB). However, its utility for routine …
Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies
Background High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in
sub-Saharan Africa, compared to Europe and North America, is well documented. Longer …
sub-Saharan Africa, compared to Europe and North America, is well documented. Longer …
The cursed duet today: Tuberculosis and HIV-coinfection
The tuberculosis (TB) and HIV syndemic continues to rage and are a major public health
concern worldwide. This deadly association raises complexity and represent a significant …
concern worldwide. This deadly association raises complexity and represent a significant …
Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis
The high burden of tuberculosis (TB) among patients accessing antiretroviral treatment
(ART) services in resource-limited settings is a major cause of morbidity and mortality and is …
(ART) services in resource-limited settings is a major cause of morbidity and mortality and is …
Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis
M Schito, TF Peter, S Cavanaugh… - Journal of Infectious …, 2012 - academic.oup.com
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue
to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis …
to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis …
Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial
GL Calligaro, LS Zijenah, JG Peter… - The Lancet Infectious …, 2017 - thelancet.com
Background Inadequate case detection results in high levels of undiagnosed tuberculosis in
sub-Saharan Africa. Data for the effect of new diagnostic tools when used for community …
sub-Saharan Africa. Data for the effect of new diagnostic tools when used for community …